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1cjc

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Current revision (23:26, 27 December 2023) (edit) (undo)
 
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<StructureSection load='1cjc' size='340' side='right'caption='[[1cjc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1cjc' size='340' side='right'caption='[[1cjc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1cjc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CJC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1cjc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CJC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adrenodoxin-NADP(+)_reductase Adrenodoxin-NADP(+) reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.6 1.18.1.6] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cjc OCA], [https://pdbe.org/1cjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cjc RCSB], [https://www.ebi.ac.uk/pdbsum/1cjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cjc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cjc OCA], [https://pdbe.org/1cjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cjc RCSB], [https://www.ebi.ac.uk/pdbsum/1cjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cjc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ADRO_BOVIN ADRO_BOVIN]] Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
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[https://www.uniprot.org/uniprot/ADRO_BOVIN ADRO_BOVIN] Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Schulz, G E]]
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[[Category: Schulz GE]]
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[[Category: Vonrhein, C]]
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[[Category: Vonrhein C]]
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[[Category: Ziegler, G A]]
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[[Category: Ziegler GA]]
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[[Category: Electron transferase]]
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[[Category: Flavoenzyme]]
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[[Category: Mad analysis]]
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[[Category: Oxidoreductase]]
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Current revision

STRUCTURE OF ADRENODOXIN REDUCTASE OF MITOCHONDRIAL P450 SYSTEMS

PDB ID 1cjc

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