7pk5

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'''Unreleased structure'''
 
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The entry 7pk5 is ON HOLD until Paper Publication
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==Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein)==
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<StructureSection load='7pk5' size='340' side='right'caption='[[7pk5]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
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Authors: Fadel, J., Schirmer, T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7pk5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PK5 FirstGlance]. <br>
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Description: Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein)
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pk5 OCA], [https://pdbe.org/7pk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pk5 RCSB], [https://www.ebi.ac.uk/pdbsum/7pk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pk5 ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Schirmer, T]]
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== Function ==
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[[Category: Fadel, J]]
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[[https://www.uniprot.org/uniprot/PDEL_ECOLI PDEL_ECOLI]] Acts both as an enzyme and as a c-di-GMP sensor to couple transcriptional activity to the c-di-GMP status of the cell (PubMed:26553851). Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG (PubMed:15995192, PubMed:24451384, PubMed:26553851). Also acts as a transcription factor to control its own expression (PubMed:26553851).<ref>PMID:15995192</ref> <ref>PMID:24451384</ref> <ref>PMID:26553851</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Fadel J]]
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[[Category: Schirmer T]]

Revision as of 16:34, 7 September 2022

Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein)

PDB ID 7pk5

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