This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7byi
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ==== | + | ==Structure of SHMT2 in complex with CBX== |
| - | <StructureSection load='7byi' size='340' side='right'caption='[[7byi]]' scene=''> | + | <StructureSection load='7byi' size='340' side='right'caption='[[7byi]], [[Resolution|resolution]] 2.76Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7byi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BYI FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Chen Y]] |
| + | [[Category: Li L]] | ||
| + | [[Category: Lu D]] | ||
| + | [[Category: Su D]] | ||
| + | [[Category: Zhang C]] | ||
Revision as of 05:44, 7 June 2023
Structure of SHMT2 in complex with CBX
| |||||||||||
Categories: Homo sapiens | Large Structures | Chen Y | Li L | Lu D | Su D | Zhang C
