7p3s
From Proteopedia
(Difference between revisions)
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==Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 12== | ==Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 12== | ||
| - | <StructureSection load='7p3s' size='340' side='right'caption='[[7p3s]]' scene=''> | + | <StructureSection load='7p3s' size='340' side='right'caption='[[7p3s]], [[Resolution|resolution]] 1.55Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P3S FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7p3s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P3S FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p3s OCA], [https://pdbe.org/7p3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p3s RCSB], [https://www.ebi.ac.uk/pdbsum/7p3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p3s ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.546Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5IB:~{N}-[2-methoxy-5-(oxidanylcarbamoyl)phenyl]dibenzofuran-4-carboxamide'>5IB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p3s OCA], [https://pdbe.org/7p3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p3s RCSB], [https://www.ebi.ac.uk/pdbsum/7p3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p3s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A5H660_SCHMA A5H660_SCHMA] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Schistosoma mansoni]] | ||
[[Category: Romier C]] | [[Category: Romier C]] | ||
[[Category: Shaik TB]] | [[Category: Shaik TB]] | ||
Current revision
Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 12
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