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7pgw
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==H3K36 tri-methylated nucleosome LEDGF PWWP domain complex pose 2== | |
| - | + | <StructureSection load='7pgw' size='340' side='right'caption='[[7pgw]], [[Resolution|resolution]] 7.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7pgw]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PGW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ML3:2-{[(2R)-2-AMINO-2-CARBOXYETHYL]SULFANYL}-N,N,N-TRIMETHYLETHANAMINIUM'>ML3</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pgw OCA], [https://pdbe.org/7pgw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pgw RCSB], [https://www.ebi.ac.uk/pdbsum/7pgw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pgw ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Hexnerova | + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| - | [[Category: Koutna | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Poepsel | + | [[Category: Large Structures]] |
| - | [[Category: Skerlova | + | [[Category: Synthetic construct]] |
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Hexnerova R]] | ||
| + | [[Category: Koutna E]] | ||
| + | [[Category: Lux V]] | ||
| + | [[Category: Novacek J]] | ||
| + | [[Category: Poepsel S]] | ||
| + | [[Category: Skerlova J]] | ||
| + | [[Category: Srb P]] | ||
| + | [[Category: Veverka V]] | ||
Revision as of 12:29, 22 February 2023
H3K36 tri-methylated nucleosome LEDGF PWWP domain complex pose 2
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Categories: Homo sapiens | Large Structures | Synthetic construct | Xenopus laevis | Hexnerova R | Koutna E | Lux V | Novacek J | Poepsel S | Skerlova J | Srb P | Veverka V
