1rsr

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Current revision (08:26, 1 May 2024) (edit) (undo)
 
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<StructureSection load='1rsr' size='340' side='right'caption='[[1rsr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1rsr' size='340' side='right'caption='[[1rsr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1rsr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RSR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1rsr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RSR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mxr|1mxr]], [[1xik|1xik]], [[1rsv|1rsv]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rsr OCA], [https://pdbe.org/1rsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rsr RCSB], [https://www.ebi.ac.uk/pdbsum/1rsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rsr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rsr OCA], [https://pdbe.org/1rsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rsr RCSB], [https://www.ebi.ac.uk/pdbsum/1rsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rsr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
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[https://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Andersson KK]]
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[[Category: Andersson, K K]]
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[[Category: Andersson ME]]
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[[Category: Andersson, M E]]
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[[Category: Hogbom M]]
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[[Category: Hogbom, M]]
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[[Category: Nordlund P]]
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[[Category: Nordlund, P]]
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[[Category: Rinaldo-Matthis A]]
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[[Category: Rinaldo-Matthis, A]]
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[[Category: Sjoberg BM]]
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[[Category: Sjoberg, B M]]
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[[Category: Azide]]
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[[Category: Diiron]]
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[[Category: Oxidoreductase]]
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[[Category: Oxygen activation]]
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Current revision

azide complex of the diferrous F208A mutant R2 subunit of ribonucleotide reductase

PDB ID 1rsr

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