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6xcu
From Proteopedia
(Difference between revisions)
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==NMR structure of Ost4V23D, a critical mutant of Ost4, in DPC micelles== | ==NMR structure of Ost4V23D, a critical mutant of Ost4, in DPC micelles== | ||
| - | <StructureSection load='6xcu' size='340' side='right'caption='[[6xcu | + | <StructureSection load='6xcu' size='340' side='right'caption='[[6xcu]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6xcu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[6xcu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_YJM789 Saccharomyces cerevisiae YJM789]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XCU FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xcu OCA], [https://pdbe.org/6xcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xcu RCSB], [https://www.ebi.ac.uk/pdbsum/6xcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xcu ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xcu OCA], [https://pdbe.org/6xcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xcu RCSB], [https://www.ebi.ac.uk/pdbsum/6xcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xcu ProSAT]</span></td></tr> | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OST4_YEAST OST4_YEAST] Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. OST4 is required for recruitment of OST3 or OST6 to the OST complex. It is essential for cell growth at 37 but not at 25 degrees Celsius. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Baker's yeast]] | ||
| - | [[Category: Dolichyl-diphosphooligosaccharide--protein glycotransferase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae YJM789]] |
| - | [[Category: | + | [[Category: Chaudhary BP]] |
| - | + | ||
Current revision
NMR structure of Ost4V23D, a critical mutant of Ost4, in DPC micelles
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