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1kfp

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Current revision (06:02, 5 July 2023) (edit) (undo)
 
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==Solution structure of the antimicrobial 18-residue gomesin==
==Solution structure of the antimicrobial 18-residue gomesin==
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<StructureSection load='1kfp' size='340' side='right'caption='[[1kfp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1kfp' size='340' side='right'caption='[[1kfp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1kfp]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KFP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1kfp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthoscurria_gomesiana Acanthoscurria gomesiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KFP FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kfp OCA], [https://pdbe.org/1kfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kfp RCSB], [https://www.ebi.ac.uk/pdbsum/1kfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kfp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kfp OCA], [https://pdbe.org/1kfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kfp RCSB], [https://www.ebi.ac.uk/pdbsum/1kfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kfp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GOME_ACAGO GOME_ACAGO]] Active against several Gram-positive bacteria such as Bacillus spp, Staphylococcus spp and E.faecalis, several Gram-negative bacteria such as E.coli, K.pneumoniae, P.aeruginosa and Salmonella spp, filamentous fungi such as N.crassa, T.viridae and yeasts such as C.albicans. It is active against the parasite L.amazonensis as well. It shows hemolytic activity.<ref>PMID:10942757</ref>
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[https://www.uniprot.org/uniprot/GOME_ACAGO GOME_ACAGO] Active against several Gram-positive bacteria such as Bacillus spp, Staphylococcus spp and E.faecalis, several Gram-negative bacteria such as E.coli, K.pneumoniae, P.aeruginosa and Salmonella spp, filamentous fungi such as N.crassa, T.viridae and yeasts such as C.albicans. It is active against the parasite L.amazonensis as well. It shows hemolytic activity.<ref>PMID:10942757</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acanthoscurria gomesiana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bulet, P]]
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[[Category: Bulet P]]
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[[Category: Caille, A]]
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[[Category: Caille A]]
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[[Category: Daffre, S]]
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[[Category: Daffre S]]
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[[Category: Mandard, N]]
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[[Category: Mandard N]]
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[[Category: Vovelle, F]]
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[[Category: Vovelle F]]
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[[Category: Antibiotic]]
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[[Category: Beta-sheet]]
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[[Category: Disulfide bridge]]
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[[Category: Hairpin-like]]
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Current revision

Solution structure of the antimicrobial 18-residue gomesin

PDB ID 1kfp

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