Hydroxysteroid dehydrogenase 3D structures
From Proteopedia
(Difference between revisions)
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**[[1fjh]] - CtHSD – ''Comamonas testosterone''<BR /> | **[[1fjh]] - CtHSD – ''Comamonas testosterone''<BR /> | ||
**[[4is2]] – CsHSD – ''Clostridium scindens''<br /> | **[[4is2]] – CsHSD – ''Clostridium scindens''<br /> | ||
| + | **[[7p36]] - LkHSD – ''Lactobacillus kefiri<''br /> | ||
*''3-α HSD binary complex'' | *''3-α HSD binary complex'' | ||
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**[[2dkn]] - HSD + NAD – ''Pseudomonas''<BR /> | **[[2dkn]] - HSD + NAD – ''Pseudomonas''<BR /> | ||
**[[4is3]] - CsHSD + NAD<br /> | **[[4is3]] - CsHSD + NAD<br /> | ||
| + | **[[7ejh]], [[7eji]], [[7ejj]], [[7vdo]], [[7vet]] - LkHSD (mutant`) + NADP <br /> | ||
*''3-α HSD ternary complex'' | *''3-α HSD ternary complex'' | ||
| Line 39: | Line 41: | ||
**[[7eny]] – EcHSD – ''Escherichia coli''<br /> | **[[7eny]] – EcHSD – ''Escherichia coli''<br /> | ||
**[[1ahh]] – EcHSD + NAD <BR /> | **[[1ahh]] – EcHSD + NAD <BR /> | ||
| - | **[[1ahi]], [[1fmc]] – EcHSD + hydroxysteroid + NAD | + | **[[1ahi]], [[1fmc]] – EcHSD + hydroxysteroid + NAD<br /> |
| + | **[[5epo]] – HSD + NADP – ''Clostridium sardiniese''<br /> | ||
| + | |||
| + | *7-beta HSD | ||
| + | |||
| + | **[[5fyd]] – CaHSD – ''Collinsella aerofaciens<''br /> | ||
| + | **[[5gt9]] – CaHSD + NADP<br /> | ||
*20-α HSD or AKR1C1 | *20-α HSD or AKR1C1 | ||
| + | **[[6a7a]] – hHSD + NADP + inhibitor<br /> | ||
**[[1q5m]] - raHSD + NADP – rabbit | **[[1q5m]] - raHSD + NADP – rabbit | ||
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**[[3c3u]], [[3nty]] - hHSD + inhibitor + NADP<BR /> | **[[3c3u]], [[3nty]] - hHSD + inhibitor + NADP<BR /> | ||
**[[3gug]] - hHSD (mutant) + inhibitor + NADP<BR /> | **[[3gug]] - hHSD (mutant) + inhibitor + NADP<BR /> | ||
| + | **[[6ijx]] – hHSD + NADP + meclofenamic acid<br /> | ||
**[[1q13]] - raHSD + hydroxysteroid + NADP<BR /> | **[[1q13]] - raHSD + hydroxysteroid + NADP<BR /> | ||
| + | |||
| + | *20-beta HSD | ||
| + | |||
| + | **[[6m9u]] – BaHSD – ''Bifidobacterium adolescentis''<br /> | ||
| + | **[[6ow4]] – BaHSD + NADP <br /> | ||
*11-β HSD or corticosteroid 11-β-dehydrogenase 1 | *11-β HSD or corticosteroid 11-β-dehydrogenase 1 | ||
| Line 66: | Line 81: | ||
**[[2bel]] - hHSD 1 + hydroxysteroid + NADP<BR /> | **[[2bel]] - hHSD 1 + hydroxysteroid + NADP<BR /> | ||
| - | **[[2irw]], [[2ilt]], [[4bb5]], [[4bb6]] - hHSD 1 + inhibitor + NADP<BR /> | + | **[[2irw]], [[2ilt]], [[4bb5]], [[4bb6]], [[4yyz]] - hHSD 1 + inhibitor + NADP<BR /> |
| - | **[[2rbe]], [[3byz]], [[3bzu]], [[3ch6]], [[3czr]], [[3d3e]], [[3d4n]], [[3d5q]], [[3ey4]], [[3frj]], [[3hfg]], [[3fco]], [[3h6k]], [[3oq1]], [[3pdj]], [[3tfq]], [[3qqp]], [[4c7j]], [[4c7k]], [[4p38]], [[5pgu]], [[5pgv]], [[5pgw]], [[5pgx]], [[5pgy]], [[5pgz]], [[5pii]], [[5pij]] - hHSD 1 (mutant) + inhibitor + NADP<BR /> | + | **[[2rbe]], [[3byz]], [[3bzu]], [[3ch6]], [[3czr]], [[3d3e]], [[3d4n]], [[3d5q]], [[3ey4]], [[3frj]], [[3hfg]], [[3fco]], [[3h6k]], [[3oq1]], [[3pdj]], [[3tfq]], [[3qqp]], [[4c7j]], [[4c7k]], [[4p38]], [[5pgu]], [[5pgv]], [[5pgw]], [[5pgx]], [[5pgy]], [[5pgz]], [[5pii]], [[5pij]], [[5qii]] - hHSD 1 (mutant) + inhibitor + NADP<BR /> |
**[[6nj7]] - hHSD 1 + colleic acid + NAP<br /> | **[[6nj7]] - hHSD 1 + colleic acid + NAP<br /> | ||
**[[3g49]] - gpHSD catalytic domain + inhibitor + NADP<BR /> | **[[3g49]] - gpHSD catalytic domain + inhibitor + NADP<BR /> | ||
**[[1y5r]], [[3gmd]] - mHSD 1 + hydroxysteroid + NADP<BR /> | **[[1y5r]], [[3gmd]] - mHSD 1 + hydroxysteroid + NADP<BR /> | ||
| - | **[[4k26]] - mHSD 1 + inhibitor + NADP<br /> | + | **[[4k26]], [[5qij]] - mHSD 1 + inhibitor + NADP<br /> |
**[[4nmh]] - mHSD 1 (mutant) + inhibitor + NADP<br /> | **[[4nmh]] - mHSD 1 (mutant) + inhibitor + NADP<br /> | ||
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**[[6mnc]] – hHSD 1 + estrone<br /> | **[[6mnc]] – hHSD 1 + estrone<br /> | ||
**[[1fdv]] - hHSD 1 (mutant) + NAD<BR /> | **[[1fdv]] - hHSD 1 (mutant) + NAD<BR /> | ||
| - | **[[1qyv]] - hHSD 1 + NADP<BR /> | + | **[[1equ]], [[1qyv]] - hHSD 1 + NADP<BR /> |
**[[1i5r]], [[6dtp]] - hHSD 1 + inhibitor<br /> | **[[1i5r]], [[6dtp]] - hHSD 1 + inhibitor<br /> | ||
**[[1zbq]] - hHSD 4 + NAD<BR /> | **[[1zbq]] - hHSD 4 + NAD<BR /> | ||
| + | **[[2o23]] – hHSD 10 + NAD<br /> | ||
**[[5l7t]], [[5l7w]], [[5l7y]], [[5icm]], [[5en4]] - hHSD 14 + inhibitor<br /> | **[[5l7t]], [[5l7w]], [[5l7y]], [[5icm]], [[5en4]] - hHSD 14 + inhibitor<br /> | ||
**[[6h0m]], [[6hno]], [[5js6]], [[5jsf]] - hHSD 14 (mutant) + NAD<br /> | **[[6h0m]], [[6hno]], [[5js6]], [[5jsf]] - hHSD 14 (mutant) + NAD<br /> | ||
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**[[3hb5]], [[6cge]] - hHSD 1 + inhibitor + NADP<BR /> | **[[3hb5]], [[6cge]] - hHSD 1 + inhibitor + NADP<BR /> | ||
**[[4hfr]], [[4hx5]], [[4iju]], [[4ijv]], [[4ijw]], [[4k1l]], [[6cgc]] - hHSD 1 (mutant) + inhibitor + NADP<br /> | **[[4hfr]], [[4hx5]], [[4iju]], [[4ijv]], [[4ijw]], [[4k1l]], [[6cgc]] - hHSD 1 (mutant) + inhibitor + NADP<br /> | ||
| - | **[[6mne]] – hHSD 1 + NADP + estrone<br /> | + | **[[6mne]], [[7x3z]] – hHSD 1 + NADP + estrone<br /> |
**[[5o42]], [[5o43]], [[5o6o]], [[5o6x]], [[5o6z]], [[5o72]] - hHSD 14 + inhibitor + NAD<br /> | **[[5o42]], [[5o43]], [[5o6o]], [[5o6x]], [[5o6z]], [[5o72]] - hHSD 14 + inhibitor + NAD<br /> | ||
**[[5hs6]] - hHSD + NAD + estrone<br /> | **[[5hs6]] - hHSD + NAD + estrone<br /> | ||
Revision as of 08:44, 25 May 2023
3D structures of hydroxysteroid dehydrogenase
Updated on 25-May-2023
For 3-α HSD type 2 see Prostaglandin F synthase
For 17-β HSD type 5 or AKR1C3 see Prostaglandin F synthase
