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Insulin receptor 3D structures
From Proteopedia
(Difference between revisions)
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Insulin receptor; domains: L1-CR 28-337; 1-3 28-512; transmembrane 940-988; TK 1005-1310; | + | *Insulin receptor; domains: L1-CR 28-337; 1-3 28-512; transmembrane 940-988; TK 1005-1310; Ectodomain 28-1382 |
**[[1irk]] – hIR TK domain – human<br /> | **[[1irk]] – hIR TK domain – human<br /> | ||
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**[[2hr7]] – hIR domains 1-3<br /> | **[[2hr7]] – hIR domains 1-3<br /> | ||
**[[4xst]] – hIR L1-CR domains <br /> | **[[4xst]] – hIR L1-CR domains <br /> | ||
| - | **[[2mfr]] – hIR transmembrane domain - NMR<br /> | + | **[[2mfr]], [[7pht]] – hIR transmembrane domain - NMR<br /> |
| - | *Insulin receptor | + | *Insulin receptor complexes |
**[[5j3h]] – hIR L1-CR domains + antibody + peptide<br /> | **[[5j3h]] – hIR L1-CR domains + antibody + peptide<br /> | ||
| + | **[[7kd6]] – hIR L1-CR domains + Scfv<br /> | ||
**[[4xss]] – hIR L1-CR domains + insulin-like growth factor 1<br /> | **[[4xss]] – hIR L1-CR domains + insulin-like growth factor 1<br /> | ||
**[[3w12]] – hIR L1-CR domain + insulin + antibody<br /> | **[[3w12]] – hIR L1-CR domain + insulin + antibody<br /> | ||
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**[[1rqq]] – hIR TK domain (mutant) + adaptor protein PS<br /> | **[[1rqq]] – hIR TK domain (mutant) + adaptor protein PS<br /> | ||
**[[6ce7]], [[6ce9]], [[6ceb]] – hIR + insulin <ref>PMID:29512653</ref> <br /> | **[[6ce7]], [[6ce9]], [[6ceb]] – hIR + insulin <ref>PMID:29512653</ref> <br /> | ||
| - | **[[6pxv]], [[6pxw]], [[6sof]], [[7bw7]], [[7bw8]], [[7bwa]] – hIR + insulin – Cryo EM<br /> | + | **[[6pxv]], [[6pxw]], [[6sof]], [[7bw7]], [[7bw8]], [[7bwa]], [[7md4]], [[7md5]], [[7mqo]], [[7mqr]], [[7mqs]], [[7qid]], [[8guy]] – hIR ectodomain + insulin – Cryo EM<br /> |
| - | **[[ | + | **[[7u6d]], [[7u6e]] – hIR ectodomain + agonist – Cryo EM<br /> |
| + | **[[7yq3]], [[7yq4]], [[7yq5]], [[7yq6]] – hIR ectodomain + DNA – Cryo EM<br /> | ||
| + | **[[7pg0]], [[7pg2]], [[7pg3]], [[7pg4]], [[7sl1]], [[7sl2]], [[7sl3]], [[7sl4]], [[7sl6]], [[7sl7]], [[7sth]], [[7sti]], [[7stj]], [[7stk]] – hIR + insulin – Cryo EM<br /> | ||
| + | **[[8dtl]], [[8dtm]] – hIR + insulin mimetic – Cryo EM<br /> | ||
| + | **[[7s8v]] – hIR ectodomain + IGF-I receptor – Cryo EM<br /> | ||
| + | **[[7s0q]] – hIR ectodomain + IGF-I receptor + IGF-I – Cryo EM<br /> | ||
| + | **[[6hn4]], [[6hn5]] - hIR + insulin <br /> | ||
**[[5kqv]] – hIR + insulin + antibody<br /> | **[[5kqv]] – hIR + insulin + antibody<br /> | ||
**[[6vep]] – hIR + insulin + antibody – Cryo EM<br /> | **[[6vep]] – hIR + insulin + antibody – Cryo EM<br /> | ||
| + | **[[8eyx]], [[8eyy]], [[8ez0]] – mIR (mutant) + insulin – Cryo EM<br /> | ||
**[[6veq]] – IR + insulin + antibody – ''Conus geographus'' - Cryo EM<br /> | **[[6veq]] – IR + insulin + antibody – ''Conus geographus'' - Cryo EM<br /> | ||
Current revision
3D structures of insulin receptor
Updated on 31-May-2023
