6zg9
From Proteopedia
(Difference between revisions)
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==Structure of M1-StaR-T4L in complex with GSK1034702 at 2.5A== | ==Structure of M1-StaR-T4L in complex with GSK1034702 at 2.5A== | ||
| - | <StructureSection load='6zg9' size='340' side='right'caption='[[6zg9]]' scene=''> | + | <StructureSection load='6zg9' size='340' side='right'caption='[[6zg9]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZG9 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6zg9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZG9 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zg9 OCA], [https://pdbe.org/6zg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zg9 RCSB], [https://www.ebi.ac.uk/pdbsum/6zg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zg9 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QK2:7-fluoranyl-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1~{H}-benzimidazol-2-one'>QK2</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zg9 OCA], [https://pdbe.org/6zg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zg9 RCSB], [https://www.ebi.ac.uk/pdbsum/6zg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zg9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/ACM1_HUMAN ACM1_HUMAN]] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Muscarinic acetylcholine receptor|Muscarinic acetylcholine receptor]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Cooke | + | [[Category: Lysozyme]] |
| - | [[Category: Rucktooa P]] | + | [[Category: Cooke, R M]] |
| + | [[Category: Rucktooa, P]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Membrane protein]] | ||
Revision as of 06:26, 1 December 2021
Structure of M1-StaR-T4L in complex with GSK1034702 at 2.5A
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