7d6o
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
==Oxidized structure of bovine xanthine oxidoreductase bound with oxypurinol.== | ==Oxidized structure of bovine xanthine oxidoreductase bound with oxypurinol.== | ||
- | <StructureSection load='7d6o' size='340' side='right'caption='[[7d6o]]' scene=''> | + | <StructureSection load='7d6o' size='340' side='right'caption='[[7d6o]], [[Resolution|resolution]] 1.99Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7D6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7D6O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7d6o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7dnv 7dnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7D6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7D6O FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d6o OCA], [https://pdbe.org/7d6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d6o RCSB], [https://www.ebi.ac.uk/pdbsum/7d6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d6o ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=141:OXYPURINOL'>141</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MOS:DIOXOTHIOMOLYBDENUM(VI)+ION'>MOS</scene>, <scene name='pdbligand=MTE:PHOSPHONIC+ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER'>MTE</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d6o OCA], [https://pdbe.org/7d6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d6o RCSB], [https://www.ebi.ac.uk/pdbsum/7d6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d6o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/XDH_BOVIN XDH_BOVIN] Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Xanthine dehydrogenase 3D structures|Xanthine dehydrogenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Bos taurus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Okamoto K]] | [[Category: Okamoto K]] |
Revision as of 09:55, 24 November 2022
Oxidized structure of bovine xanthine oxidoreductase bound with oxypurinol.
|