This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7d6o
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Oxidized structure of bovine xanthine oxidoreductase bound with oxypurinol.== | ==Oxidized structure of bovine xanthine oxidoreductase bound with oxypurinol.== | ||
| - | <StructureSection load='7d6o' size='340' side='right'caption='[[7d6o]]' scene=''> | + | <StructureSection load='7d6o' size='340' side='right'caption='[[7d6o]], [[Resolution|resolution]] 1.99Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7D6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7D6O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7d6o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7dnv 7dnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7D6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7D6O FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d6o OCA], [https://pdbe.org/7d6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d6o RCSB], [https://www.ebi.ac.uk/pdbsum/7d6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d6o ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=141:OXYPURINOL'>141</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MOS:DIOXOTHIOMOLYBDENUM(VI)+ION'>MOS</scene>, <scene name='pdbligand=MTE:PHOSPHONIC+ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER'>MTE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d6o OCA], [https://pdbe.org/7d6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d6o RCSB], [https://www.ebi.ac.uk/pdbsum/7d6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d6o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/XDH_BOVIN XDH_BOVIN] Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Xanthine dehydrogenase 3D structures|Xanthine dehydrogenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Okamoto K]] | [[Category: Okamoto K]] | ||
Revision as of 09:55, 24 November 2022
Oxidized structure of bovine xanthine oxidoreductase bound with oxypurinol.
| |||||||||||
