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Ion channels 3D structures

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**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
**[[6hj3]], [[6hjb]], [[6hji]], [[6hja]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
**[[6hj3]], [[6hjb]], [[6hji]], [[6hja]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
 +
**[[6v03]], [[6v0b]] - ELIC – ''Dickeya dadantii'' – Cryo EM<br />
* Cyclic Nucleotide-Gated channel
* Cyclic Nucleotide-Gated channel
 +
**[[7lg1]] – hCNGA1 (mutant) – Cryo EM<br />
 +
**[[7lft]] – hCNGA1 + cGMP – Cryo EM<br />
 +
**[[7lfw]], [[7lfx]], [[7lfy]] – hCNGA1 (mutant) + cGMP – Cryo EM<br />
 +
**[[3swf]] - bCNGC CLZ domain <br />
**[[2zd9]], [[3beh]] - MlCNGC - ''Mesorhizobium loti''<br />
**[[2zd9]], [[3beh]] - MlCNGC - ''Mesorhizobium loti''<br />
**[[4chv]], [[4chw]] – MlCNGC – Cryo EM<br />
**[[4chv]], [[4chw]] – MlCNGC – Cryo EM<br />
Line 210: Line 215:
**[[3co2]], [[4muv]], [[3clp]], [[1u12]] - MlCNGC ligand-binding domain (mutant) <br />
**[[3co2]], [[4muv]], [[3clp]], [[1u12]] - MlCNGC ligand-binding domain (mutant) <br />
**[[3cl1]], [[2k0g]] - MlCNGC ligand-binding domain + cyclic nucleotide<br />
**[[3cl1]], [[2k0g]] - MlCNGC ligand-binding domain + cyclic nucleotide<br />
-
**[[3swf]] - CNGC CLZ domain - bovine<br />
 
**[[5h3o]] – CeCNGC – Cryo EM<br />
**[[5h3o]] – CeCNGC – Cryo EM<br />
 +
**[[6wej]], [[6wek]], [[6wel]] – CeCNGC + cGMP – Cryo EM<br />
 +
**[[6cju]], [[6vxz]], [[6vy0]] – StCNGC + cAMP – ''Spitochaeta thermophila'' - Cryo EM<br />
 +
**[[6cjq]] – StCNGC - Cryo EM<br />
 +
**[[6cjt]] – StCNGC + cGMP - Cryo EM<br />
*Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
*Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
-
**[[3etq]], [[3ffq]], [[3u0z]], [[3u10]], [[3u11]] - mCNGC C-terminal<br />
 
-
**[[1q3e]], [[1q43]], [[1q5o]] - mCNGC 2 fragment + nucleotide<br />
 
-
**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
 
-
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
 
**[[5u6o]], [[5u6p]], [[6uqf]], [[6uqg]] – hCNGC 1 – Cryo EM<br />
**[[5u6o]], [[5u6p]], [[6uqf]], [[6uqg]] – hCNGC 1 – Cryo EM<br />
**[[2mpf]] – hCNGC 2 ligand-binding domain - NMR<br />
**[[2mpf]] – hCNGC 2 ligand-binding domain - NMR<br />
-
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
 
**[[3swy]] – hCNGC 3 CLZ domain<br />
**[[3swy]] – hCNGC 3 CLZ domain<br />
**[[6gyn]] – hCNGC 4 – Cryo EM<br />
**[[6gyn]] – hCNGC 4 – Cryo EM<br />
Line 230: Line 233:
**[[4kl1]] – hCNGC 4 C terminal + nucleotide<br />
**[[4kl1]] – hCNGC 4 C terminal + nucleotide<br />
**[[4nvp]] – hCNGC 4 ligand-binding domain + 7-CH-cAMP<br />
**[[4nvp]] – hCNGC 4 ligand-binding domain + 7-CH-cAMP<br />
 +
**[[7nmn]], [[7np3]] – rCNGC 4 – Cryo EM<br />
 +
**[[7np4]] – rCNGC 4 + cAMP – Cryo EM<br />
 +
**[[3etq]], [[3ffq]], [[3u0z]], [[3u10]], [[3u11]] - mCNGC C-terminal<br />
 +
**[[1q3e]], [[1q43]], [[1q5o]] - mCNGC 2 fragment + nucleotide<br />
 +
**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
 +
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
 +
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
-
* Acid sensitive ion channel
+
* Acid sensing ion channel
 +
**[[6l6i]], [[6l6n]], [[6l6p]] – hASC <br />
 +
**[[7cfs]] – hASC – Cryo EM<br />
 +
**[[7cft]] – hASC + toxin – Cryo EM<br />
 +
**[[7rnn]] – hASC + nanobody – Cryo EM<br />
**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
 +
**[[6x9h]] – cASC + modulator<br />
-
* ATP-Gated channel (AGC)
+
* ATP-Gated P2X channel (AGC) or purinoceptor
-
**[[3h9v]], [[3i5d]] – zeAGC <br />
+
**[[5vj]], [[5svt]] – hAGC P2X3 <br />
-
**[[4dw0]] – zeAGC (mutant)<br />
+
**[[5yve]] – hAGC P2X3 + modulator<br />
-
**[[4dw1]] – zeAGC + ATP<br />
+
**[[5svq]], [[5svr]] – hAGC P2X3 + antagonist<br />
 +
**[[5svm]], [[5svp]] – hAGC P2X3 + agonist<br />
 +
**[[5svk]], [[5svl]], [[6ah4]], [[6ah5]] – hAGC P2X3 + ATP<br />
 +
**[[5xw6]] – cAGC P2X7 + antagonist<br />
 +
**[[3h9v]], [[3i5d]] – zeAGC P2X4<br />
 +
**[[4dw0]] – zeAGC P2X4 (mutant)<br />
 +
**[[4dw1]] – zeAGC P2X4 + ATP<br />
* Proton channel or matrix protein 2
* Proton channel or matrix protein 2
Line 249: Line 270:
**[[2kih]], [[2kwx]] – IVproton channel (mutant)<br />
**[[2kih]], [[2kwx]] – IVproton channel (mutant)<br />
**[[3bkd]], [[4qkm]], [[4qkl]], [[4qkc]], [[4qk7]], [[3lbw]], [[5ttc]], [[5um1]], [[5joo]] - IVproton channel transmembrane domain<br />
**[[3bkd]], [[4qkm]], [[4qkl]], [[4qkc]], [[4qk7]], [[3lbw]], [[5ttc]], [[5um1]], [[5joo]] - IVproton channel transmembrane domain<br />
-
**[[1nyj]], [[1mp6]], [[2kad]] - IVproton channel transmembrane domain - NMR<br />
+
**[[1nyj]], [[1mp6]], [[2kad]], [[6pvr]], [[6pvt]] - IVproton channel transmembrane domain - NMR<br />
-
**[[5c02]], [[4rwc]], [[4rwb]], [[2kih]] - IVproton channel transmembrane domain (mutant)<br />
+
**[[5c02]], [[4rwc]], [[4rwb]], [[2kih]], [[6mjh]] - IVproton channel transmembrane domain (mutant)<br />
**[[2n70]] - IVproton channel transmembrane domain (mutant) - NMR<br />
**[[2n70]] - IVproton channel transmembrane domain (mutant) - NMR<br />
**[[6bkk]], [[6bkl]], [[6bmz]], [[6boc]] - IVproton channel transmembrane domain + drug<br />
**[[6bkk]], [[6bkl]], [[6bmz]], [[6boc]] - IVproton channel transmembrane domain + drug<br />
Line 256: Line 277:
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
**[[2rlf]] - IVproton channel + inhibitor - NMR<br />
**[[2rlf]] - IVproton channel + inhibitor - NMR<br />
-
**[[3c9j]] - IVproton channel transmembrane domain + inhibitor<br />
+
**[[3c9j]], [[6oug]] - IVproton channel transmembrane domain + inhibitor<br />
 +
**[[6nv1]] - IVproton channel transmembrane domain (mutant) + inhibitor<br />
* Voltage-gated hydrogen channel (VGHC)
* Voltage-gated hydrogen channel (VGHC)

Revision as of 10:14, 7 October 2021

3D structures of ion channels

Updated on 07-October-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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