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Kinesin 3D Structures

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Line 38: Line 38:
**[[2heh]], [[4ubf]], [[5y05]] – hKIF2C<br />
**[[2heh]], [[4ubf]], [[5y05]] – hKIF2C<br />
**[[2gry]] – hKIF2+ADP<br />
**[[2gry]] – hKIF2+ADP<br />
 +
**[[6bbn]] – hKIF2A MD + Tubulin + Darpin<br />
**[[5mio]] – hKIF2C MD + Tubulin <br />
**[[5mio]] – hKIF2C MD + Tubulin <br />
**[[1v8j]], [[5xja]], [[5xjb]] – mKIF2C MD+Mg-ADP<br />
**[[1v8j]], [[5xja]], [[5xjb]] – mKIF2C MD+Mg-ADP<br />
Line 66: Line 67:
**[[4a14]] – hKIF7 MD <br />
**[[4a14]] – hKIF7 MD <br />
**[[2xt3]] – hKIF7 MD (mutant)<br />
**[[2xt3]] – hKIF7 MD (mutant)<br />
 +
**[[6mlr]] – hKIF7 MD + Tubulin + GTP + GDP + ANP – Cryo EM<br />
 +
**[[6mlq]] – hKIF7 MD + Tubulin + GTP + GDP + ADP – Cryo EM<br />
*KIF9 or kinesin-9
*KIF9 or kinesin-9
Line 74: Line 77:
**[[3j2u]] – hKIF10A head domain – Cryo EM<br />
**[[3j2u]] – hKIF10A head domain – Cryo EM<br />
-
**[[6b0c]] – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
+
**[[6b0c]], [[6b0l]] – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
 +
**[[6vpp]] – DmKlp61F + tubulin + GTP + GDP + Mg – Cryo EM<br />
 +
**[[6vpo]] – DmKlp61F + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
 +
**[[6b0i]] – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
-
*KIF11 or kinesin-5
+
*KIF11 or kinesin-5 or Eg5
[[4b7b]] - hKIF11 (mutant) + ADP + Co + Cd <br />
[[4b7b]] - hKIF11 (mutant) + ADP + Co + Cd <br />
[[3ken]], [[2wog]], [[2x2r]], [[2xae]], [[4bbg]] - hKIF11 +S-trityl-L-cysteine derivative + ADP + Mg<br />
[[3ken]], [[2wog]], [[2x2r]], [[2xae]], [[4bbg]] - hKIF11 +S-trityl-L-cysteine derivative + ADP + Mg<br />
**[[3wpn]] - hKIF11 +inhibitor <br />
**[[3wpn]] - hKIF11 +inhibitor <br />
-
[[2uyi]], [[2uym]], [[2gm1]], [[2pg2]], [[2fme]], [[2x7d]], [[2x7c]], [[2ieh]], [[3cjo]], [[2g1q]], [[2fl2]], [[2fl6]], [[1yrs]], [[2q2y]], [[2fky]], [[2q2z]], [[3k3b]], [[2x7e]], [[4a50]], [[4a51]], [[3zcw]] - hKIF11+inhibitor +ADP + Mg<br />
+
[[2uyi]], [[2uym]], [[2gm1]], [[2pg2]], [[2fme]], [[2x7d]], [[2x7c]], [[2ieh]], [[3cjo]], [[2g1q]], [[2fl2]], [[2fl6]], [[1yrs]], [[2q2y]], [[2fky]], [[2q2z]], [[3k3b]], [[2x7e]], [[4a50]], [[4a51]], [[3zcw]], [[6g6y]], [[6g6z]], [[6hkx]], [[6hky]] - hKIF11+inhibitor +ADP + Mg<br />
[[4bxn]], [[4as7]] - hKIF11+inhibitor +ADP + Cd<br />
[[4bxn]], [[4as7]] - hKIF11+inhibitor +ADP + Cd<br />
[[3l9h]] - hKIF11+inhibitor +ADP <br />
[[3l9h]] - hKIF11+inhibitor +ADP <br />
Line 89: Line 95:
[[3hqd]] - hKIF11 +AMPPNP+Mg<br />
[[3hqd]] - hKIF11 +AMPPNP+Mg<br />
[[1ii6]], [[4a1z]], [[4a28]] - hKIF11 +ADP+Mg<br />
[[1ii6]], [[4a1z]], [[4a28]] - hKIF11 +ADP+Mg<br />
-
**[[4zca]] - hKIF11 (mutant) +ADP+Mg<br />
+
**[[4zca]], [[6tle]], [[6trl]], [[6y1i]] - hKIF11 (mutant) +ADP+Mg<br />
[[3k5e]] - hKIF11 +ADP+enastrol + Mg<br />
[[3k5e]] - hKIF11 +ADP+enastrol + Mg<br />
**[[6zpi]] – hKIF11 MD + tubulin + GDP + GTP + Mg – Cryo EM<br />
**[[6zpi]] – hKIF11 MD + tubulin + GDP + GTP + Mg – Cryo EM<br />
Line 97: Line 103:
**[[6ta4]] – hKIF11 MD + tubulin + G2P + ANP + Mg – Cryo EM<br />
**[[6ta4]] – hKIF11 MD + tubulin + G2P + ANP + Mg – Cryo EM<br />
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] – KIF MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM<br />
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] – KIF MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM<br />
-
**[[5mm4]], [[5mm7]] – UmKIF + tubulin + GDP + GTP + ANP + taxol – Ustilago maydis – Cryo EM<br />
+
**[[6s8m]] – fyKIFCut7 MD + tubulin + GDP + GTP + ANP – Cryo EM<br />
 +
**[[5mm4]], [[5mm7]] – UmKIF + tubulin + GDP + GTP + ANP + taxol – ''Ustilago maydis'' – Cryo EM<br />
*KIF13A, KIF13B or kinesin-3
*KIF13A, KIF13B or kinesin-3
Line 111: Line 118:
**[[3kin]], [[2kin]] – rKIF MD <br />
**[[3kin]], [[2kin]] – rKIF MD <br />
**[[6a1z]] – rKIF13B<br />
**[[6a1z]] – rKIF13B<br />
-
**[[6a20]] – rKIF13B (mutant)<br />
+
**[[5zbs]], [[6a20]] – rKIF13B (mutant)<br />
-
**[[5zbs]] – rKIF13B (mutant)<br />
+
**[[7d8v]] – rKIF13B (mutant) + ADP<br />
**[[5zbr]] – rKIF13B + AMPPNP<br />
**[[5zbr]] – rKIF13B + AMPPNP<br />
*KIF14 or kinesin-3
*KIF14 or kinesin-3
 +
**[[6wwe]], [[6wwi]], [[6wwt]] – hKIF14 MD + Tubulin + GTP + GDP – Cryo EM<br />
 +
**[[6wwf]], [[6wwh]], [[6wwg]], [[6wwj]], [[6wwk]], [[6wwl]], [[6wwm]], [[6wwn]], [[6wwo]], [[6wwp]], [[6wwq]], [[6wwr]], [[6wws]], [[6wwu]], [[6wwv]], [[7lvr]] – mKIF14 MD + Tubulin + nucleotides – Cryo EM<br />
**[[1f9t]], [[1f9u]], [[1f9v]], [[1f9w]], [[3kar]] - yKar3 MD (mutant) – yeast<br />
**[[1f9t]], [[1f9u]], [[1f9v]], [[1f9w]], [[3kar]] - yKar3 MD (mutant) – yeast<br />
**[[4etp]] - yKar3 MD (mutant) + VIK1<br />
**[[4etp]] - yKar3 MD (mutant) + VIK1<br />
Line 123: Line 132:
**[[4bn2]] – hKIF15 MD<br />
**[[4bn2]] – hKIF15 MD<br />
 +
**[[7ryp]] – hKIF15 MD + KIF-binding protein – Cryo EM<br />
*KIF16B or kinesin-3
*KIF16B or kinesin-3
**[[2v14]] – hKIF16B<br />
**[[2v14]] – hKIF16B<br />
 +
**[[6ee0]] – hKIF16B PX domain 1026-1156<br />
*KIF18A, KIF18B or kinesin-8
*KIF18A, KIF18B or kinesin-8
Line 134: Line 145:
**[[5ocu]] - hKIF18A MD + tubulin + GTP + GDP + ANP<br />
**[[5ocu]] - hKIF18A MD + tubulin + GTP + GDP + ANP<br />
**[[5ogc]] - hKIF18A MD + tubulin + GTP + GDP + taxol<br />
**[[5ogc]] - hKIF18A MD + tubulin + GTP + GDP + taxol<br />
 +
**[[7rsi]] – hKIF18A MD + KIF-binding protein + ADP – Cryo EM<br />
*KIF19A or kinesin-8
*KIF19A or kinesin-8
Line 142: Line 154:
*KIF20A, KIF20B or kinesin-6
*KIF20A, KIF20B or kinesin-6
 +
**[[6yip]] – hKIF20A coiled coil domain 596-668 <br />
**[[5nd3]] – mKIF20A MD + tubulin <br />
**[[5nd3]] – mKIF20A MD + tubulin <br />
**[[5nd2]], [[5nd4]] – mKIF20A MD + tubulin + ADP <br />
**[[5nd2]], [[5nd4]] – mKIF20A MD + tubulin + ADP <br />
Line 151: Line 164:
**[[5d3a]] – hKIF21A coiled coil domain 938-1017 <br />
**[[5d3a]] – hKIF21A coiled coil domain 938-1017 <br />
 +
**[[7klj]] – hKIF21A WD-repeat domain 1324-1640 <br />
*KIF22 or kinesin-10
*KIF22 or kinesin-10
Line 168: Line 182:
**[[1n6m]] – DmKIF MD+FNL<br />
**[[1n6m]] – DmKIF MD+FNL<br />
**[[3l1c]] – DmNCD (mutant)<br />
**[[3l1c]] – DmNCD (mutant)<br />
-
**[[1ry6]] – KIF MD – ''Plasmodium falciparum''<br />
+
**[[1ry6]] – PfKIF MD – ''Plasmodium falciparum''<br />
 +
**[[7nba]] – PfKlF + tubulin + GTP + G2P + ANP + Mg – Cryo EM<br />
 +
**[[7nb8]] – PfKlF + tubulin + GTP + G2P + Mg – Cryo EM<br />
**[[1goj]] – NcKIF MD<br />
**[[1goj]] – NcKIF MD<br />
*Kinesin light chain (KLC)
*Kinesin light chain (KLC)
-
**[[5oj8]] – hKLC1 TPR domain <br />
+
**[[5oj8]], [[7ai4]], [[7aie]] – hKLC1 TPR domain <br />
-
3edt – hKLC2
+
**[[6fuz]] – hKLC1 TPR domain + nanobody<br />
-
3ceq, 3nf1 – hKLC2 TPR domain
+
**[[3edt]] – hKLC2<br />
 +
**[[3ceq]], [[3nf1]] – hKLC2 TPR domain<br />
**[[6f9i]] – hKLC2 + clcytenin peptide <br />
**[[6f9i]] – hKLC2 + clcytenin peptide <br />
**[[6fv0]] – mKLC1 TPR domain + nanobody<br />
**[[6fv0]] – mKLC1 TPR domain + nanobody<br />
**[[5ojf]] – mKLC2 TPR domain <br />
**[[5ojf]] – mKLC2 TPR domain <br />
-
**[[3zfw]], [[5fjy]], [[6ejn]] - mKLC2 TPR domain + peptide<br />
+
**[[3zfw]], [[5fjy]], [[6ejn]], [[6swu]] - mKLC2 TPR domain + peptide<br />
 +
*KCBP
*KCBP

Revision as of 10:07, 13 October 2021

3D Structures of Kinesin

Updated on 13-October-2021

4b7b - hKIF11 (mutant) + ADP + Co + Cd
3ken, 2wog, 2x2r, 2xae, 4bbg - hKIF11 +S-trityl-L-cysteine derivative + ADP + Mg
2uyi, 2uym, 2gm1, 2pg2, 2fme, 2x7d, 2x7c, 2ieh, 3cjo, 2g1q, 2fl2, 2fl6, 1yrs, 2q2y, 2fky, 2q2z, 3k3b, 2x7e, 4a50, 4a51, 3zcw, 6g6y, 6g6z, 6hkx, 6hky - hKIF11+inhibitor +ADP + Mg
4bxn, 4as7 - hKIF11+inhibitor +ADP + Cd
3l9h - hKIF11+inhibitor +ADP
1x88, 1q0b - hKIF11 +Mg + ADP+monastrol
4ap0, 4a5y - hKIF11 +MgADP + ispinesib + Mg
3hqd - hKIF11 +AMPPNP+Mg
1ii6, 4a1z, 4a28 - hKIF11 +ADP+Mg
3k5e - hKIF11 +ADP+enastrol + Mg
4aqv, 4aqw – hKIF11 (mutant) + tubulin + GDP + GTP + Mg – Cryo EM
4ck5, 4ck6, 4ck7 – hKIF11 (mutant) + tubulin + ADP + GDP + GTP + Mg – Cryo EM


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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