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1fe6

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{{STRUCTURE_1fe6| PDB=1fe6 | SCENE= }}
{{STRUCTURE_1fe6| PDB=1fe6 | SCENE= }}
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'''CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER'''
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===CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER===
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==Overview==
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The crystal structure of a polypeptide chain fragment from the surface layer protein tetrabrachion from Staphylothermus marinus has been determined at 1.8 A resolution. As proposed on the basis of the presence of 11-residue repeats, the polypeptide chain fragment forms a parallel right-handed coiled coil structure. Complementary hydrophobic interactions and complex networks of surface salt bridges result in an extremely thermostable tetrameric structure with remarkable properties. In marked contrast to left-handed coiled coil tetramers, the right-handed coiled coil reveals large hydrophobic cavities that are filled with water molecules. As a consequence, the packing of the hydrophobic core differs markedly from that of a right-handed parallel coiled coil tetramer that was designed on the basis of left-handed coiled coil structures.
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(as it appears on PubMed at http://www.pubmed.gov), where 10966648 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10966648}}
==About this Structure==
==About this Structure==
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[[Category: Stetefeld, J.]]
[[Category: Stetefeld, J.]]
[[Category: Right handed coiled coil]]
[[Category: Right handed coiled coil]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:13:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:07:11 2008''

Revision as of 00:07, 1 July 2008

Template:STRUCTURE 1fe6

CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER

Template:ABSTRACT PUBMED 10966648

About this Structure

1FE6 is a Single protein structure of sequence from Staphylothermus marinus. Full crystallographic information is available from OCA.

Reference

Crystal structure of a naturally occurring parallel right-handed coiled coil tetramer., Stetefeld J, Jenny M, Schulthess T, Landwehr R, Engel J, Kammerer RA, Nat Struct Biol. 2000 Sep;7(9):772-6. PMID:10966648

Page seeded by OCA on Tue Jul 1 03:07:11 2008

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