3h5y

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Current revision (07:16, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3h5y' size='340' side='right'caption='[[3h5y]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='3h5y' size='340' side='right'caption='[[3h5y]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3h5y]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Norwalk_calicivirus Norwalk calicivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H5Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3h5y]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Norwalk_virus Norwalk virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H5Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3bso|3bso]], [[3bsn|3bsn]], [[1sh0|1sh0]], [[3h5x|3h5x]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">polymerase ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11983 Norwalk calicivirus])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h5y OCA], [https://pdbe.org/3h5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h5y RCSB], [https://www.ebi.ac.uk/pdbsum/3h5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h5y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h5y OCA], [https://pdbe.org/3h5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h5y RCSB], [https://www.ebi.ac.uk/pdbsum/3h5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h5y ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q70ET3_9CALI Q70ET3_9CALI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Norwalk calicivirus]]
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[[Category: Norwalk virus]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Grochulski P]]
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[[Category: Grochulski, P]]
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[[Category: Machin A]]
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[[Category: Machin, A]]
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[[Category: Ng KKS]]
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[[Category: Ng, K K.S]]
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[[Category: Parra F]]
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[[Category: Parra, F]]
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[[Category: Zamyatkin DF]]
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[[Category: Zamyatkin, D F]]
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[[Category: Caliciviruse]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Protease]]
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[[Category: Rna replication]]
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[[Category: Rna-directed rna polymerase]]
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[[Category: Thiol protease]]
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[[Category: Transferase]]
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[[Category: Transferase-rna complex]]
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[[Category: Viral rna polymerase]]
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Current revision

Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2

PDB ID 3h5y

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