3l43

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Current revision (08:30, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3l43' size='340' side='right'caption='[[3l43]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
<StructureSection load='3l43' size='340' side='right'caption='[[3l43]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3l43]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L43 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3l43]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L43 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DNM3, KIAA0820 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dynamin_GTPase Dynamin GTPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.5 3.6.5.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l43 OCA], [https://pdbe.org/3l43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l43 RCSB], [https://www.ebi.ac.uk/pdbsum/3l43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l43 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l43 OCA], [https://pdbe.org/3l43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l43 RCSB], [https://www.ebi.ac.uk/pdbsum/3l43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l43 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DYN3_HUMAN DYN3_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).
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[https://www.uniprot.org/uniprot/DYN3_HUMAN DYN3_HUMAN] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dynamin GTPase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Crombet, L]]
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[[Category: Crombet L]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Guan, X]]
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[[Category: Guan X]]
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[[Category: Nedyalkova, L]]
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[[Category: Nedyalkova L]]
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[[Category: Park, H]]
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[[Category: Park H]]
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[[Category: Structural genomic]]
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[[Category: Tempel W]]
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[[Category: Tempel, W]]
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[[Category: Tong Y]]
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[[Category: Tong, Y]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Yang S]]
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[[Category: Yang, S]]
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[[Category: Cytoskeleton]]
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[[Category: Endocytosis]]
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[[Category: Gtp-binding]]
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[[Category: Hydrolase]]
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[[Category: Microtubule]]
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[[Category: Motor protein]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Sgc]]
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Current revision

Crystal structure of the dynamin 3 GTPase domain bound with GDP

PDB ID 3l43

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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