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3l7k

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Current revision (08:32, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3l7k' size='340' side='right'caption='[[3l7k]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='3l7k' size='340' side='right'caption='[[3l7k]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3l7k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staeq Staeq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3l7k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis_RP62A Staphylococcus epidermidis RP62A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2G:[CYTIDINE-5-PHOSPHATE]+GLYCERYLPHOSPHORIC+ACID+ESTER'>C2G</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EDT:{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC+ACID'>EDT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3l7i|3l7i]], [[3l7j|3l7j]], [[3l7l|3l7l]], [[3l7m|3l7m]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2G:[CYTIDINE-5-PHOSPHATE]+GLYCERYLPHOSPHORIC+ACID+ESTER'>C2G</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EDT:{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC+ACID'>EDT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SERP1960, tagF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 STAEQ])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7k OCA], [https://pdbe.org/3l7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7k RCSB], [https://www.ebi.ac.uk/pdbsum/3l7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7k OCA], [https://pdbe.org/3l7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7k RCSB], [https://www.ebi.ac.uk/pdbsum/3l7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7k ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TAGF_STAEQ TAGF_STAEQ] Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length.<ref>PMID:20400947</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staeq]]
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[[Category: Staphylococcus epidermidis RP62A]]
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[[Category: Lovering, A L]]
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[[Category: Lovering AL]]
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[[Category: Strynadka, N C.J]]
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[[Category: Strynadka NCJ]]
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[[Category: Gt-b fold]]
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[[Category: Monotopic membrane protein]]
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[[Category: Structural protein]]
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Current revision

Structure of the Wall Teichoic Acid Polymerase TagF, H444N + CDPG (15 minute soak)

PDB ID 3l7k

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