This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1w57

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:16, 13 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1w57' size='340' side='right'caption='[[1w57]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
<StructureSection load='1w57' size='340' side='right'caption='[[1w57]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1w57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"campylobacter_fetus_subsp._jejuni"_smibert_1974 "campylobacter fetus subsp. jejuni" smibert 1974]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W57 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1w57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W57 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1w55|1w55]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w57 OCA], [https://pdbe.org/1w57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w57 RCSB], [https://www.ebi.ac.uk/pdbsum/1w57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w57 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w57 OCA], [https://pdbe.org/1w57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w57 RCSB], [https://www.ebi.ac.uk/pdbsum/1w57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w57 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/ISPDF_CAMJE ISPDF_CAMJE]] Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).[HAMAP-Rule:MF_01520]
+
[https://www.uniprot.org/uniprot/ISPDF_CAMJE ISPDF_CAMJE] Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).[HAMAP-Rule:MF_01520]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 29: Line 29:
</div>
</div>
<div class="pdbe-citations 1w57" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1w57" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Campylobacter fetus subsp. jejuni smibert 1974]]
+
[[Category: Campylobacter jejuni]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Bond, C S]]
+
[[Category: Bond CS]]
-
[[Category: Gabrielsen, M]]
+
[[Category: Gabrielsen M]]
-
[[Category: Hunter, W N]]
+
[[Category: Hunter WN]]
-
[[Category: Bifunctional]]
+
-
[[Category: Bifunctional enzyme]]
+
-
[[Category: Biosynthetic pathway]]
+
-
[[Category: Isoprenoid]]
+
-
[[Category: Nonmevalonate]]
+
-
[[Category: Transferase]]
+

Current revision

Structure of the Bifunctional IspDF from Campylobacter jejuni containing Zn

PDB ID 1w57

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w57"
Personal tools