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1w74
From Proteopedia
(Difference between revisions)
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<StructureSection load='1w74' size='340' side='right'caption='[[1w74]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='1w74' size='340' side='right'caption='[[1w74]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1w74]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1w74]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W74 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w74 OCA], [https://pdbe.org/1w74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w74 RCSB], [https://www.ebi.ac.uk/pdbsum/1w74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w74 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w74 OCA], [https://pdbe.org/1w74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w74 RCSB], [https://www.ebi.ac.uk/pdbsum/1w74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w74 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PPIA_MYCTU PPIA_MYCTU] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.<ref>PMID:15479239</ref> <ref>PMID:17141764</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | + | [[Category: Henriksson LM]] | |
| - | [[Category: Henriksson | + | [[Category: Johansson P]] |
| - | [[Category: Johansson | + | [[Category: Mowbray SL]] |
| - | [[Category: Mowbray | + | [[Category: Unge T]] |
| - | [[Category: Unge | + | |
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Current revision
X-ray structure of peptidyl-prolyl cis-trans isomerase A, PpiA, Rv0009, from Mycobacterium tuberculosis.
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