This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1u5f

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:43, 14 February 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1u5f' size='340' side='right'caption='[[1u5f]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1u5f' size='340' side='right'caption='[[1u5f]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1u5f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5F FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1u5f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5F FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u5e|1u5e]], [[1u5g|1u5g]], [[1u5d|1u5d]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCAP2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5f OCA], [https://pdbe.org/1u5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5f RCSB], [https://www.ebi.ac.uk/pdbsum/1u5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5f OCA], [https://pdbe.org/1u5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5f RCSB], [https://www.ebi.ac.uk/pdbsum/1u5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5f ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SKAP2_MOUSE SKAP2_MOUSE] May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.<ref>PMID:11063873</ref> <ref>PMID:15894167</ref> <ref>PMID:16135797</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 19: Line 20:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5f ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5f ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Mus musculus]]
-
[[Category: Eck, M J]]
+
[[Category: Eck MJ]]
-
[[Category: Neel, B G]]
+
[[Category: Neel BG]]
-
[[Category: Swanson, K D]]
+
[[Category: Swanson KD]]
-
[[Category: Tang, Y]]
+
[[Category: Tang Y]]
-
[[Category: Artefactual dimerization induced by vector-derived sequence]]
+
-
[[Category: Ph domain of skap-hom]]
+
-
[[Category: Signaling protein]]
+

Current revision

Crystal Structure of the PH Domain of SKAP-Hom with 8 Vector-derived N-terminal Residues

PDB ID 1u5f

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1u5f"
Personal tools