This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vrs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:41, 23 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1vrs' size='340' side='right'caption='[[1vrs]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='1vrs' size='340' side='right'caption='[[1vrs]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1vrs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecow3 Ecow3]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1se1 1se1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VRS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1vrs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._W3110 Escherichia coli str. K-12 substr. W3110]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1se1 1se1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VRS FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DSBD, DIPZ, CYCZ, CUTA2, B4136 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316407 ECOW3])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vrs OCA], [https://pdbe.org/1vrs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vrs RCSB], [https://www.ebi.ac.uk/pdbsum/1vrs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vrs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vrs OCA], [https://pdbe.org/1vrs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vrs RCSB], [https://www.ebi.ac.uk/pdbsum/1vrs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vrs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/DSBD_ECOLI DSBD_ECOLI]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.[HAMAP-Rule:MF_00399]
+
[https://www.uniprot.org/uniprot/DSBD_ECOLI DSBD_ECOLI] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.[HAMAP-Rule:MF_00399]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 36: Line 35:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ecow3]]
+
[[Category: Escherichia coli str. K-12 substr. W3110]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Protein-disulfide reductase]]
+
[[Category: Brunisholz R]]
-
[[Category: Brunisholz, R]]
+
[[Category: Capitani G]]
-
[[Category: Capitani, G]]
+
[[Category: Frei P]]
-
[[Category: Frei, P]]
+
[[Category: Glockshuber R]]
-
[[Category: Glockshuber, R]]
+
[[Category: Grauschopf U]]
-
[[Category: Grauschopf, U]]
+
[[Category: Gruetter MG]]
-
[[Category: Gruetter, M G]]
+
[[Category: Rozhkova A]]
-
[[Category: Rozhkova, A]]
+
[[Category: Stirnimann CU]]
-
[[Category: Stirnimann, C U]]
+
-
[[Category: Disulfide-linked]]
+
-
[[Category: Dsbd]]
+
-
[[Category: Immunoglobulin-like]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Thioredoxin-like]]
+

Current revision

Crystal structure of the disulfide-linked complex between the N-terminal and C-terminal domain of the electron transfer catalyst DsbD

PDB ID 1vrs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vrs"
Personal tools