1fh1

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[[Image:1fh1.gif|left|200px]]
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{{STRUCTURE_1fh1| PDB=1fh1 | SCENE= }}
{{STRUCTURE_1fh1| PDB=1fh1 | SCENE= }}
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'''BACKBONE FOLD OF NODF'''
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===BACKBONE FOLD OF NODF===
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==Overview==
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Over the next few years, various genome projects will sequence many new genes and yield many new gene products. Many of these products will have no known function and little, if any, sequence homology to existing proteins. There is reason to believe that a rapid determination of a protein fold, even at low resolution, can aid in the identification of function and expedite the determination of structure at higher resolution. Recently devised NMR methods of measuring residual dipolar couplings provide one route to the determination of a fold. They do this by allowing the alignment of previously identified secondary structural elements with respect to each other. When combined with constraints involving loops connecting elements or other short-range experimental distance information, a fold is produced. We illustrate this approach to protein fold determination on (15)N-labeled Eschericia coli acyl carrier protein using a limited set of (15)N-(1)H and (1)H-(1)H dipolar couplings. We also illustrate an approach using a more extended set of heteronuclear couplings on a related protein, (13)C, (15)N-labeled NodF protein from Rhizobium leguminosarum.
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The line below this paragraph, {{ABSTRACT_PUBMED_11090286}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11090286 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11090286}}
==About this Structure==
==About this Structure==
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1FH1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhizobium_leguminosarum Rhizobium leguminosarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FH1 OCA].
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1FH1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhizobium_leguminosarum Rhizobium leguminosarum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FH1 OCA].
==Reference==
==Reference==
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[[Category: Protein backbone fold]]
[[Category: Protein backbone fold]]
[[Category: Root nodulation factor]]
[[Category: Root nodulation factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:18:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:14:14 2008''

Revision as of 00:14, 1 July 2008

Image:1fh1.png

Template:STRUCTURE 1fh1

BACKBONE FOLD OF NODF

Template:ABSTRACT PUBMED 11090286

About this Structure

1FH1 is a Single protein structure of sequence from Rhizobium leguminosarum. Full experimental information is available from OCA.

Reference

Rapid determination of protein folds using residual dipolar couplings., Fowler CA, Tian F, Al-Hashimi HM, Prestegard JH, J Mol Biol. 2000 Dec 1;304(3):447-60. PMID:11090286

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