3f8a

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<StructureSection load='3f8a' size='340' side='right'caption='[[3f8a]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='3f8a' size='340' side='right'caption='[[3f8a]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3f8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3f8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=LSR:1,3,3-TRIMETHYL-2-[(1E,3E)-3-METHYLPENTA-1,3-DIEN-1-YL]CYCLOHEXENE'>LSR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3f9d|3f9d]], [[3cr6|3cr6]], [[3fa6|3fa6]], [[3fa7|3fa7]], [[3fa8|3fa8]], [[3fa9|3fa9]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=LSR:1,3,3-TRIMETHYL-2-[(1E,3E)-3-METHYLPENTA-1,3-DIEN-1-YL]CYCLOHEXENE'>LSR</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRABP2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8a OCA], [https://pdbe.org/3f8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8a RCSB], [https://www.ebi.ac.uk/pdbsum/3f8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8a OCA], [https://pdbe.org/3f8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8a RCSB], [https://www.ebi.ac.uk/pdbsum/3f8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
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[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Geiger, J H]]
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[[Category: Geiger JH]]
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[[Category: Jia, X]]
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[[Category: Jia X]]
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[[Category: C15-aldehyde]]
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[[Category: Crabpii]]
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[[Category: Nucleus]]
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[[Category: Protonated schiff base]]
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[[Category: Retinal]]
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[[Category: Retinoic acid]]
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[[Category: Retinoid]]
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[[Category: Retinol-binding]]
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[[Category: Transport]]
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[[Category: Transport protein]]
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[[Category: Vitamin some]]
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Revision as of 06:42, 6 September 2023

Crystal Structure of the R132K:R111L:L121E:R59W Mutant of Cellular Retinoic Acid-Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.95 Angstrom resolution.

PDB ID 3f8a

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