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3fhg

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Current revision (06:46, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3fhg' size='340' side='right'caption='[[3fhg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3fhg' size='340' side='right'caption='[[3fhg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fhg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FHG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fhg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FHG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3fhf|3fhf]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">1451601, MJ0724, ogg, SSO0904 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fhg OCA], [https://pdbe.org/3fhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fhg RCSB], [https://www.ebi.ac.uk/pdbsum/3fhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fhg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fhg OCA], [https://pdbe.org/3fhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fhg RCSB], [https://www.ebi.ac.uk/pdbsum/3fhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fhg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/OGG1_SULSO OGG1_SULSO]] Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites).[HAMAP-Rule:MF_00241]
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[https://www.uniprot.org/uniprot/OGG1_SACS2 OGG1_SACS2] Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).[HAMAP-Rule:MF_00241]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 35091]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Doublie, S]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Faucher, F]]
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[[Category: Doublie S]]
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[[Category: 8-oxog]]
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[[Category: Faucher F]]
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[[Category: 8-oxoguanine]]
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[[Category: Dna damage]]
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[[Category: Dna repair]]
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[[Category: Glycosidase]]
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[[Category: Glycosylase]]
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[[Category: Helix-hairpin-helix]]
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[[Category: Hydrolase]]
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[[Category: Lyase]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nuclease]]
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[[Category: Ogg]]
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[[Category: Ssogg]]
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Current revision

Crystal structure of Sulfolobus solfataricus 8-oxoguanine DNA glycosylase (SsOgg)

PDB ID 3fhg

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Proteopedia Page Contributors and Editors (what is this?)

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