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7s2p

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Current revision (16:42, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7s2p' size='340' side='right'caption='[[7s2p]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='7s2p' size='340' side='right'caption='[[7s2p]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7s2p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S2P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7s2p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S2P FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7s2n|7s2n]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s2p OCA], [https://pdbe.org/7s2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s2p RCSB], [https://www.ebi.ac.uk/pdbsum/7s2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s2p ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s2p OCA], [https://pdbe.org/7s2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s2p RCSB], [https://www.ebi.ac.uk/pdbsum/7s2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s2p ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4E4E1_TRYCC Q4E4E1_TRYCC]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glucokinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Antonio, E L.D]]
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[[Category: Trypanosoma cruzi strain CL Brener]]
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[[Category: Carey, S M]]
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[[Category: Carey SM]]
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[[Category: Chruszcz, M]]
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[[Category: Chruszcz M]]
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[[Category: Daneshian, L]]
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[[Category: D'Antonio EL]]
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[[Category: Nettles, R B]]
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[[Category: Daneshian L]]
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[[Category: Chagas disease]]
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[[Category: Nettles RB]]
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[[Category: Transferase]]
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[[Category: Trypanosoma cruzi]]
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Current revision

Crystal structure of the F337L mutation of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN

PDB ID 7s2p

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