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2izs
From Proteopedia
(Difference between revisions)
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<StructureSection load='2izs' size='340' side='right'caption='[[2izs]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='2izs' size='340' side='right'caption='[[2izs]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2izs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2izs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZS FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRQ:{[4-AMINO-2-(3-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-FLUOROPHENYL)METHANONE'>BRQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRQ:{[4-AMINO-2-(3-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-FLUOROPHENYL)METHANONE'>BRQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr> | |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izs OCA], [https://pdbe.org/2izs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izs RCSB], [https://www.ebi.ac.uk/pdbsum/2izs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izs ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izs OCA], [https://pdbe.org/2izs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izs RCSB], [https://www.ebi.ac.uk/pdbsum/2izs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izs ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/KC1G3_HUMAN KC1G3_HUMAN] Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Arrowsmith C]] | |
| - | [[Category: Arrowsmith | + | [[Category: Bunkoczi G]] |
| - | [[Category: Bunkoczi | + | [[Category: Das S]] |
| - | [[Category: Das | + | [[Category: Debreczeni JE]] |
| - | [[Category: Debreczeni | + | [[Category: Edwards A]] |
| - | + | [[Category: Fedorov O]] | |
| - | [[Category: Edwards | + | [[Category: Gileadi O]] |
| - | [[Category: Fedorov | + | [[Category: Knapp S]] |
| - | [[Category: Gileadi | + | [[Category: Rellos P]] |
| - | [[Category: Knapp | + | [[Category: Salah E]] |
| - | [[Category: Rellos | + | [[Category: Savitsky P]] |
| - | [[Category: Salah | + | [[Category: Sundstrom M]] |
| - | [[Category: Savitsky | + | [[Category: Weigelt J]] |
| - | [[Category: Sundstrom | + | [[Category: Von Delft F]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
Structure of casein kinase gamma 3 in complex with inhibitor
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bunkoczi G | Das S | Debreczeni JE | Edwards A | Fedorov O | Gileadi O | Knapp S | Rellos P | Salah E | Savitsky P | Sundstrom M | Weigelt J | Von Delft F
