1wmw

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Current revision (13:32, 13 March 2024) (edit) (undo)
 
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<StructureSection load='1wmw' size='340' side='right'caption='[[1wmw]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='1wmw' size='340' side='right'caption='[[1wmw]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1wmw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WMW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1wmw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WMW FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wmw OCA], [https://pdbe.org/1wmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wmw RCSB], [https://www.ebi.ac.uk/pdbsum/1wmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wmw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wmw TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wmw OCA], [https://pdbe.org/1wmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wmw RCSB], [https://www.ebi.ac.uk/pdbsum/1wmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wmw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wmw TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SMD0_THET8 Q5SMD0_THET8]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wmw ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wmw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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Geranylgeranyl diphosphate (GGPP) synthase from Thermus thermophilus HB8 was expressed in Escherichia coli, purified to homogeneity and crystallized both as the recombinant native protein and its selenomethionine (SeMet) derivative. Well diffracting crystals of these proteins were obtained belonging to the tetragonal space group P4(1) or P4(3), with unit-cell parameters a = b = 139.88, c = 73.37 A. There were two homodimers in the asymmetric unit. A native data set was collected to 1.55 A resolution and a data set suitable for MAD phasing was collected to 2.40 A resolution on beamline BL40B2 at SPring-8.
 
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Expression, purification, crystallization and preliminary X-ray studies of geranylgeranyl diphosphate synthase from Thermus thermophilus HB8.,Nishio K, Nodake Y, Hamada K, Suto K, Nakagawa N, Kuramitsu S, Miura K Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):178-80. Epub 2003, Dec 18. PMID:14684922<ref>PMID:14684922</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 1wmw" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thet8]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Hamada, K]]
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[[Category: Hamada K]]
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[[Category: Kawamoto, M]]
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[[Category: Kawamoto M]]
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[[Category: Kuramitu, S]]
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[[Category: Kuramitu S]]
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[[Category: Miura, K]]
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[[Category: Miura K]]
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[[Category: Nakagawa, N]]
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[[Category: Nakagawa N]]
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[[Category: Nishio, K]]
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[[Category: Nishio K]]
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[[Category: Nodake, Y]]
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[[Category: Nodake Y]]
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[[Category: Structural genomic]]
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[[Category: Suto K]]
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[[Category: Suto, K]]
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[[Category: Ggpp]]
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[[Category: Prenyl diphosphate synthase]]
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[[Category: Rsgi]]
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[[Category: Thermus]]
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[[Category: Transferase]]
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Current revision

Crystal structure of geranulgeranyl diphosphate synthase from Thermus thermophilus

PDB ID 1wmw

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