1wsw

From Proteopedia

(Difference between revisions)

Revision as of 07:59, 25 October 2023

Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, dimer, semiquinone state

Structural highlights

1wsw is a 1 chain structure with sequence from Desulfovibrio vulgaris. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.69Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FLAV_DESVH Low-potential electron donor to a number of redox enzymes.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The mutant S64C of the short-chain flavodoxin from Desulfovibrio vulgaris has been designed to introduce an accessible and reactive group on the protein surface. Crystals have been obtained of both the monomeric and homodimeric forms of the protein, with the cofactor FMN in either the oxidized or the one electron-reduced (semiquinone) state, and the structures have been determined to high resolution. The redox properties of the different species have been investigated and the variations observed with respect to wild type have been related to the structural changes induced by the mutation and S-S bridge formation.

Redox properties and crystal structures of a Desulfovibrio vulgaris flavodoxin mutant in the monomeric and homodimeric forms.,Fantuzzi A, Artali R, Bombieri G, Marchini N, Meneghetti F, Gilardi G, Sadeghi SJ, Cavazzini D, Rossi GL Biochim Biophys Acta. 2009 Mar;1794(3):496-505. Epub 2008 Dec 11. PMID:19118653^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Fantuzzi A, Artali R, Bombieri G, Marchini N, Meneghetti F, Gilardi G, Sadeghi SJ, Cavazzini D, Rossi GL. Redox properties and crystal structures of a Desulfovibrio vulgaris flavodoxin mutant in the monomeric and homodimeric forms. Biochim Biophys Acta. 2009 Mar;1794(3):496-505. Epub 2008 Dec 11. PMID:19118653 doi:10.1016/j.bbapap.2008.11.026

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wsw"

@@ Line 3: / Line 3: @@
 <StructureSection load='1wsw' size='340' side='right'caption='[[1wsw]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1wsw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_29579 Atcc 29579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WSW FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1wsw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WSW FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1wsb|1wsb]], [[1xyv|1xyv]], [[1xyy|1xyy]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wsw OCA], [https://pdbe.org/1wsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wsw RCSB], [https://www.ebi.ac.uk/pdbsum/1wsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wsw ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/FLAV_DESVH FLAV_DESVH]] Low-potential electron donor to a number of redox enzymes.
+[https://www.uniprot.org/uniprot/FLAV_DESVH FLAV_DESVH] Low-potential electron donor to a number of redox enzymes.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 36: / Line 36: @@
 __TOC__
 </StructureSection>
-[[Category: Atcc 29579]]
+[[Category: Desulfovibrio vulgaris]]
 [[Category: Large Structures]]
-[[Category: Artali, R]]
+[[Category: Artali R]]
-[[Category: Bombieri, G]]
+[[Category: Bombieri G]]
-[[Category: Cavazzini, D]]
+[[Category: Cavazzini D]]
-[[Category: Gilardi, G]]
+[[Category: Gilardi G]]
-[[Category: Marchini, N]]
+[[Category: Marchini N]]
-[[Category: Meneghetti, F]]
+[[Category: Meneghetti F]]
-[[Category: Rossi, G L]]
+[[Category: Rossi GL]]
-[[Category: Dimer]]
-[[Category: Electron transport]]
-[[Category: Flavodoxin]]
-[[Category: S64c mutant]]
-[[Category: Semireduced form]]

1wsw

From Proteopedia

Revision as of 07:59, 25 October 2023

Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, dimer, semiquinone state

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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