1ypn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:39, 9 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1ypn' size='340' side='right'caption='[[1ypn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1ypn' size='340' side='right'caption='[[1ypn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1ypn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YPN FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1ypn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YPN FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydroxymethylbilane_synthase Hydroxymethylbilane synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.61 2.5.1.61] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ypn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypn OCA], [https://pdbe.org/1ypn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ypn RCSB], [https://www.ebi.ac.uk/pdbsum/1ypn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ypn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypn OCA], [https://pdbe.org/1ypn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ypn RCSB], [https://www.ebi.ac.uk/pdbsum/1ypn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/HEM3_ECOLI HEM3_ECOLI]] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260]
+
[https://www.uniprot.org/uniprot/HEM3_ECOLI HEM3_ECOLI] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 25: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacillus coli migula 1895]]
+
[[Category: Escherichia coli]]
-
[[Category: Hydroxymethylbilane synthase]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Carr, P D]]
+
[[Category: Carr PD]]
-
[[Category: Cassetta, A]]
+
[[Category: Cassetta A]]
-
[[Category: Habash, J]]
+
[[Category: Habash J]]
-
[[Category: Haedener, A]]
+
[[Category: Haedener A]]
-
[[Category: Helliwell, J R]]
+
[[Category: Helliwell JR]]
-
[[Category: Nieh, Y P]]
+
[[Category: Nieh YP]]
-
[[Category: Niemann, A C]]
+
[[Category: Niemann AC]]
-
[[Category: Raftery, J]]
+
[[Category: Raftery J]]
-
[[Category: Thompson, A W]]
+
[[Category: Thompson AW]]
-
[[Category: Ursby, T]]
+
[[Category: Ursby T]]
-
[[Category: Wulff, M]]
+
[[Category: Wulff M]]
-
[[Category: All alpha/beta]]
+
-
[[Category: Biosynthesis of linear tetrapyrrole]]
+
-
[[Category: Transferase]]
+

Current revision

REDUCED FORM HYDROXYMETHYLBILANE SYNTHASE (K59Q MUTANT) CRYSTAL STRUCTURE AFTER 2 HOURS IN A FLOW CELL DETERMINED BY TIME-RESOLVED LAUE DIFFRACTION

PDB ID 1ypn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools