6wh6

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<StructureSection load='6wh6' size='340' side='right'caption='[[6wh6]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='6wh6' size='340' side='right'caption='[[6wh6]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6wh6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WH6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6wh6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WH6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UQ1:UBIQUINONE-1'>UQ1</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UQ1:UBIQUINONE-1'>UQ1</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SQOR, SQRDL, CGI-44 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wh6 OCA], [https://pdbe.org/6wh6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wh6 RCSB], [https://www.ebi.ac.uk/pdbsum/6wh6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wh6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wh6 OCA], [https://pdbe.org/6wh6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wh6 RCSB], [https://www.ebi.ac.uk/pdbsum/6wh6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wh6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SQOR_HUMAN SQOR_HUMAN]] Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro).<ref>PMID:22852582</ref>
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[https://www.uniprot.org/uniprot/SQOR_HUMAN SQOR_HUMAN] Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro).<ref>PMID:22852582</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6wh6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6wh6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
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*[[3D structures of sulfide quinone oxidoreductase|3D structures of sulfide quinone oxidoreductase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Banerjee, R]]
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[[Category: Banerjee R]]
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[[Category: Cho, U S]]
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[[Category: Cho US]]
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[[Category: Moon, S]]
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[[Category: Moon S]]
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[[Category: Oxidoreductase]]
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Revision as of 14:24, 18 October 2023

Crystal structure of human sulfide quinone oxidoreductase in complex with coenzyme Q (cyanide soaked)

PDB ID 6wh6

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