Corticosteroids
From Proteopedia
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<StructureSection load='' size='350' side='right' caption='FMN containing pentaerythritol tetranitrate reductase complex with prednisone (PDB entry [[1h61]])' scene='49/490063/Cv/1'> | <StructureSection load='' size='350' side='right' caption='FMN containing pentaerythritol tetranitrate reductase complex with prednisone (PDB entry [[1h61]])' scene='49/490063/Cv/1'> | ||
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, [[glucocorticoids]] and [[mineralocorticoids]], are involved in a wide range of physiological processes. | Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, [[glucocorticoids]] and [[mineralocorticoids]], are involved in a wide range of physiological processes. | ||
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| + | Prednisone and its derivatives have some mineralocorticoid action in addition to the glucocorticoid effec | ||
*[[Glucocorticoids]] | *[[Glucocorticoids]] | ||
*[[Mineralocorticoids]] | *[[Mineralocorticoids]] | ||
Revision as of 12:58, 9 November 2021
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References
- ↑ Barna TM, Khan H, Bruce NC, Barsukov I, Scrutton NS, Moody PC. Crystal structure of pentaerythritol tetranitrate reductase: "flipped" binding geometries for steroid substrates in different redox states of the enzyme. J Mol Biol. 2001 Jul 6;310(2):433-47. PMID:11428899 doi:10.1006/jmbi.2001.4779
