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1xki

From Proteopedia

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Current revision (14:11, 9 May 2024) (edit) (undo)
 
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<StructureSection load='1xki' size='340' side='right'caption='[[1xki]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1xki' size='340' side='right'caption='[[1xki]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xki]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xki]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LCN1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xki OCA], [https://pdbe.org/1xki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xki RCSB], [https://www.ebi.ac.uk/pdbsum/1xki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xki ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xki OCA], [https://pdbe.org/1xki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xki RCSB], [https://www.ebi.ac.uk/pdbsum/1xki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xki ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LCN1_HUMAN LCN1_HUMAN]] Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
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[https://www.uniprot.org/uniprot/LCN1_HUMAN LCN1_HUMAN] Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Breustedt, D A]]
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[[Category: Breustedt DA]]
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[[Category: Korndoerfer, I P]]
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[[Category: Korndoerfer IP]]
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[[Category: Redl, B]]
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[[Category: Redl B]]
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[[Category: Skerra, A]]
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[[Category: Skerra A]]
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[[Category: Beta barrel]]
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[[Category: Ligand binding protein]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of human tear lipocalin/von Ebners gland protein

PDB ID 1xki

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