This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2f27
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2f27' size='340' side='right'caption='[[2f27]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='2f27' size='340' side='right'caption='[[2f27]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2f27]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2f27]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F27 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f27 OCA], [https://pdbe.org/2f27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f27 RCSB], [https://www.ebi.ac.uk/pdbsum/2f27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f27 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f27 OCA], [https://pdbe.org/2f27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f27 RCSB], [https://www.ebi.ac.uk/pdbsum/2f27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f27 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN] Hydrolyzes sialylated compounds. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 26: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chavas | + | [[Category: Chavas LMG]] |
| - | [[Category: Fusi | + | [[Category: Fusi P]] |
| - | [[Category: Kato | + | [[Category: Kato R]] |
| - | [[Category: Monti | + | [[Category: Monti E]] |
| - | [[Category: Tettamanti | + | [[Category: Tettamanti G]] |
| - | [[Category: Tringali | + | [[Category: Tringali C]] |
| - | [[Category: Venerando | + | [[Category: Venerando B]] |
| - | [[Category: Wakatsuki | + | [[Category: Wakatsuki S]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor
| |||||||||||
Categories: Homo sapiens | Large Structures | Chavas LMG | Fusi P | Kato R | Monti E | Tettamanti G | Tringali C | Venerando B | Wakatsuki S
