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6xjo

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Current revision (14:53, 18 October 2023) (edit) (undo)
 
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<StructureSection load='6xjo' size='340' side='right'caption='[[6xjo]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6xjo' size='340' side='right'caption='[[6xjo]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6xjo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XJO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6xjo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XJO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATL3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xjo OCA], [https://pdbe.org/6xjo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xjo RCSB], [https://www.ebi.ac.uk/pdbsum/6xjo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xjo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xjo OCA], [https://pdbe.org/6xjo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xjo RCSB], [https://www.ebi.ac.uk/pdbsum/6xjo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xjo ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/ATLA3_HUMAN ATLA3_HUMAN]] Hereditary sensory and autonomic neuropathy type 1. The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/ATLA3_HUMAN ATLA3_HUMAN] Hereditary sensory and autonomic neuropathy type 1. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ATLA3_HUMAN ATLA3_HUMAN]] GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.<ref>PMID:18270207</ref> <ref>PMID:19665976</ref>
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[https://www.uniprot.org/uniprot/ATLA3_HUMAN ATLA3_HUMAN] GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.<ref>PMID:18270207</ref> <ref>PMID:19665976</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6xjo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6xjo" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Atlastin 3D structures|Atlastin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Donnell, J P.O]]
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[[Category: O'Donnell JP]]
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[[Category: Sondermann, H]]
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[[Category: Sondermann H]]
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[[Category: Fusogen]]
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[[Category: Gtpase]]
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[[Category: Hydrolase]]
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Current revision

Human atlastin-3 (residues 1-334) bound to GDP-Mg2+ exhibits an ordered amino terminus

PDB ID 6xjo

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