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1lv3

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==Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.==
==Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.==
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<StructureSection load='1lv3' size='340' side='right'caption='[[1lv3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1lv3' size='340' side='right'caption='[[1lv3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1lv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1lv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yacG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv3 OCA], [https://pdbe.org/1lv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1lv3 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv3 OCA], [https://pdbe.org/1lv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1lv3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/YACG_ECOLI YACG_ECOLI]] Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<ref>PMID:18586829</ref>
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[https://www.uniprot.org/uniprot/YACG_ECOLI YACG_ECOLI] Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<ref>PMID:18586829</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Cort, J R]]
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[[Category: Cort JR]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Kennedy, M A]]
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[[Category: Kennedy MA]]
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[[Category: Structural genomic]]
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[[Category: Ramelot TA]]
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[[Category: Ramelot, T A]]
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[[Category: Semesi A]]
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[[Category: Semesi, A]]
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[[Category: Yee AA]]
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[[Category: Yee, A A]]
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[[Category: Antiparallel beta strand and alpha helix]]
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[[Category: C4 tetrahedral zn+2]]
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[[Category: Et92]]
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[[Category: Nesg project]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Rubredoxin knuckle]]
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[[Category: Unknown function]]
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[[Category: Zinc finger]]
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Revision as of 08:23, 14 June 2023

Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.

PDB ID 1lv3

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