2xyb

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<StructureSection load='2xyb' size='340' side='right'caption='[[2xyb]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='2xyb' size='340' side='right'caption='[[2xyb]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pycnoporus_cinnabarinus Pycnoporus cinnabarinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XYB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trametes_cinnabarina Trametes cinnabarina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XYB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AS8:ACETYLSULFATE'>AS8</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Laccase Laccase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AS8:ACETYLSULFATE'>AS8</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xyb OCA], [https://pdbe.org/2xyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xyb RCSB], [https://www.ebi.ac.uk/pdbsum/2xyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xyb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xyb OCA], [https://pdbe.org/2xyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xyb RCSB], [https://www.ebi.ac.uk/pdbsum/2xyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xyb ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q9UVQ2_PYCCI Q9UVQ2_PYCCI]
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Laccase isozymes from the white-rot basidiomycete fungi Trametes versicolor and Pycnoporus cinnabarinus were purified to apparent iso-electric homogeneity and crystallised. T. versicolor laccase crystallises in two crystal forms, both with the orthorhombic space group P2(1)2(1)2(1), which diffract to 1.9 and 2.95 A resolution, respectively. The crystals of P. cinnabarinus laccase belong to the monoclinic space group C2 and diffract to at least 2.2 A resolution. All the laccase crystals are suitable for X-ray structure determination and contain a full complement of copper ions.
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Purification, crystallisation and X-ray diffraction study of fully functional laccases from two ligninolytic fungi.,Antorini M, Herpoel-Gimbert I, Choinowski T, Sigoillot JC, Asther M, Winterhalter K, Piontek K Biochim Biophys Acta. 2002 Jan 31;1594(1):109-14. PMID:11825613<ref>PMID:11825613</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2xyb" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
*[[Laccase 3D structures|Laccase 3D structures]]
*[[Laccase 3D structures|Laccase 3D structures]]
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Laccase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pycnoporus cinnabarinus]]
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[[Category: Trametes cinnabarina]]
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[[Category: Antorini, M]]
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[[Category: Antorini M]]
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[[Category: Asther, M]]
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[[Category: Asther M]]
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[[Category: Choinowski, T]]
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[[Category: Choinowski T]]
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[[Category: Herpoel-Gimbert, I]]
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[[Category: Herpoel-Gimbert I]]
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[[Category: Piontek, K]]
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[[Category: Piontek K]]
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[[Category: Plattner, D A]]
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[[Category: Plattner DA]]
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[[Category: Sigoillot, J C]]
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[[Category: Sigoillot JC]]
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[[Category: Winterhalter, K]]
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[[Category: Winterhalter K]]
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[[Category: Blue multi-copper oxidase]]
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[[Category: Lignin degradation]]
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[[Category: Oxidoreductase]]
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[[Category: Phenol oxidase]]
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Current revision

CRYSTAL STRUCTURE OF A FULLY FUNCTIONAL LACCASE FROM THE LIGNINOLYTIC FUNGUS PYCNOPORUS CINNABARINUS

PDB ID 2xyb

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