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Nuclear receptor coactivator
From Proteopedia
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*'''NCOA3''' shows histone acetyltransferase activity.<br /> | *'''NCOA3''' shows histone acetyltransferase activity.<br /> | ||
*'''NCOA5''' is both a DNA transcription coactivator and corepressor. It interacts with steroid receptor.<br /> | *'''NCOA5''' is both a DNA transcription coactivator and corepressor. It interacts with steroid receptor.<br /> | ||
| + | See also: [[Glucocorticoids]]<br />. | ||
== Structural highlights == | == Structural highlights == | ||
*<scene name='49/494427/Cv/7'>NCOA/STAT6 transactivator domain LXXLL peptide interactions</scene>. | *<scene name='49/494427/Cv/7'>NCOA/STAT6 transactivator domain LXXLL peptide interactions</scene>. | ||
Revision as of 08:28, 10 January 2023
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3D structures of nuclear receptor coactivator
Updated on 10-January-2023
1v95 – hNCOA5 anticodon binding domain 197-313 – human - NMR
1kbh, 6es7, 6sqc – hNCOA3 1040-1086 + CREB-binding protein - NMR
2c52 – hNCOA1 residues 920-970 + CREB-binding protein - NMR
1oj5 – mNCOA1A Pas-B domain 257-367 + signal transducer and activator of transcription peptide - mouse
5y7w - mNCOA1A Pas-B domain + YL-2 peptide
References
- ↑ Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 1996 Oct;10(10):1167-77. PMID:9121485 doi:http://dx.doi.org/10.1210/mend.10.10.9121485
