Nuclear receptor coactivator

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 6: Line 6:
*'''NCOA3''' shows histone acetyltransferase activity.<br />
*'''NCOA3''' shows histone acetyltransferase activity.<br />
*'''NCOA5''' is both a DNA transcription coactivator and corepressor. It interacts with steroid receptor.<br />
*'''NCOA5''' is both a DNA transcription coactivator and corepressor. It interacts with steroid receptor.<br />
 +
See also: [[Glucocorticoids]]<br />.
== Structural highlights ==
== Structural highlights ==
*<scene name='49/494427/Cv/7'>NCOA/STAT6 transactivator domain LXXLL peptide interactions</scene>.
*<scene name='49/494427/Cv/7'>NCOA/STAT6 transactivator domain LXXLL peptide interactions</scene>.

Revision as of 08:28, 10 January 2023

Mouse nuclear receptor activator (green) complex with STAT6 transactivator domain LXXLL peptide (sky blue) and I-1 ions, 1oj5

Drag the structure with the mouse to rotate

3D structures of nuclear receptor coactivator

Updated on 10-January-2023

1v95 – hNCOA5 anticodon binding domain 197-313 – human - NMR
1kbh, 6es7, 6sqc – hNCOA3 1040-1086 + CREB-binding protein - NMR
2c52 – hNCOA1 residues 920-970 + CREB-binding protein - NMR
1oj5 – mNCOA1A Pas-B domain 257-367 + signal transducer and activator of transcription peptide - mouse
5y7w - mNCOA1A Pas-B domain + YL-2 peptide

References

  1. ↑ Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 1996 Oct;10(10):1167-77. PMID:9121485 doi:http://dx.doi.org/10.1210/mend.10.10.9121485

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Nuclear_receptor_coactivator"
Personal tools