6zuz
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==TFIIS N-terminal domain (TND) from human Elongin-A== | ==TFIIS N-terminal domain (TND) from human Elongin-A== | ||
| - | <StructureSection load='6zuz' size='340' side='right'caption='[[6zuz]]' scene=''> | + | <StructureSection load='6zuz' size='340' side='right'caption='[[6zuz]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[6zuz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZUZ FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zuz OCA], [https://pdbe.org/6zuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zuz RCSB], [https://www.ebi.ac.uk/pdbsum/6zuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zuz ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zuz OCA], [https://pdbe.org/6zuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zuz RCSB], [https://www.ebi.ac.uk/pdbsum/6zuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zuz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/ELOA1_HUMAN ELOA1_HUMAN]] SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | [Figure: see text]. | ||
| + | |||
| + | A ubiquitous disordered protein interaction module orchestrates transcription elongation.,Cermakova K, Demeulemeester J, Lux V, Nedomova M, Goldman SR, Smith EA, Srb P, Hexnerova R, Fabry M, Madlikova M, Horejsi M, De Rijck J, Debyser Z, Adelman K, Hodges HC, Veverka V Science. 2021 Nov 26;374(6571):1113-1121. doi: 10.1126/science.abe2913. Epub 2021, Nov 25. PMID:34822292<ref>PMID:34822292</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6zuz" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Veverka V]] | + | [[Category: Veverka, V]] |
| + | [[Category: Elongation factor]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 10:01, 8 December 2021
TFIIS N-terminal domain (TND) from human Elongin-A
| |||||||||||
