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5sbb
From Proteopedia
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| - | ==== | + | ==Tubulin-maytansinoid-4c-complex== |
| - | <StructureSection load='5sbb' size='340' side='right'caption='[[5sbb]]' scene=''> | + | <StructureSection load='5sbb' size='340' side='right'caption='[[5sbb]], [[Resolution|resolution]] 2.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5sbb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SBB FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sbb OCA], [https://pdbe.org/5sbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sbb RCSB], [https://www.ebi.ac.uk/pdbsum/5sbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sbb ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5JH:(1R,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl+heptanoate'>5JH</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sbb OCA], [https://pdbe.org/5sbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sbb RCSB], [https://www.ebi.ac.uk/pdbsum/5sbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sbb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | ||
| + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | ||
| + | *[[Tubulin tyrosine ligase 3D structures|Tubulin tyrosine ligase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Gallus gallus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Z- | + | [[Category: Rattus norvegicus]] |
| + | [[Category: Abel A-C]] | ||
| + | [[Category: Alvarez-Bernad B]] | ||
| + | [[Category: Boiarska Z]] | ||
| + | [[Category: Diaz JF]] | ||
| + | [[Category: Lucena-Agell D]] | ||
| + | [[Category: Marzullo P]] | ||
| + | [[Category: Passarella D]] | ||
| + | [[Category: Perez-Pena H]] | ||
| + | [[Category: Pieraccini S]] | ||
| + | [[Category: Prota AE]] | ||
| + | [[Category: Sironi M]] | ||
| + | [[Category: Steinmetz MO]] | ||
| + | [[Category: Vasile F]] | ||
Revision as of 15:29, 6 March 2024
Tubulin-maytansinoid-4c-complex
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