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6zuy
From Proteopedia
(Difference between revisions)
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==Human TFIIS N-terminal domain (TND)== | ==Human TFIIS N-terminal domain (TND)== | ||
| - | <StructureSection load='6zuy' size='340' side='right'caption='[[6zuy | + | <StructureSection load='6zuy' size='340' side='right'caption='[[6zuy]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6zuy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZUY FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6zuy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZUY FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zuy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zuy OCA], [https://pdbe.org/6zuy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zuy RCSB], [https://www.ebi.ac.uk/pdbsum/6zuy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zuy ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zuy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zuy OCA], [https://pdbe.org/6zuy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zuy RCSB], [https://www.ebi.ac.uk/pdbsum/6zuy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zuy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | + | [https://www.uniprot.org/uniprot/TCEA1_HUMAN TCEA1_HUMAN] Note=A chromosomal aberration involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1. | |
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/TCEA1_HUMAN TCEA1_HUMAN] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Veverka | + | [[Category: Veverka V]] |
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Current revision
Human TFIIS N-terminal domain (TND)
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