2cz2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='2cz2' size='340' side='right'caption='[[2cz2]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='2cz2' size='340' side='right'caption='[[2cz2]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2cz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ2 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2cz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ2 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cz3|2cz3]]</div></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz2 OCA], [https://pdbe.org/2cz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz2 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz2 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz2 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz2 OCA], [https://pdbe.org/2cz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz2 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz2 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz2 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/MAAI_MOUSE MAAI_MOUSE]] Probable bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid (By similarity).
+
[https://www.uniprot.org/uniprot/MAAI_MOUSE MAAI_MOUSE] Probable bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 27: Line 26:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Mus musculus]]
-
[[Category: Kinoshita, Y]]
+
[[Category: Kinoshita Y]]
-
[[Category: Mizohata, E]]
+
[[Category: Mizohata E]]
-
[[Category: Morita, S]]
+
[[Category: Morita S]]
-
[[Category: Nagano, K]]
+
[[Category: Nagano K]]
-
[[Category: Structural genomic]]
+
[[Category: Shirouzu M]]
-
[[Category: Shirouzu, M]]
+
[[Category: Uchikubo T]]
-
[[Category: Uchikubo, T]]
+
[[Category: Uda H]]
-
[[Category: Uda, H]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S]]
+
-
[[Category: Gst]]
+
-
[[Category: Gstz1-1]]
+
-
[[Category: Isomerase]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Transferase]]
+

Revision as of 11:32, 22 May 2024

Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from Mus musculus (form-1 crystal)

PDB ID 2cz2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cz2"
Personal tools