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Phosphoribosyltransferase 3D structures
From Proteopedia
(Difference between revisions)
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*[[7cmj]] - LdHPRT – ''Leishmania donovani''<br /> | *[[7cmj]] - LdHPRT – ''Leishmania donovani''<br /> | ||
| - | *'''Hypoxanthine-guanine phosphoribosyltransferase''' | + | *'''Hypoxanthine-guanine phosphoribosyltransferase or purine/pyrimidine PRT''' |
**[[1z7g]] - hHPRT <br /> | **[[1z7g]] - hHPRT <br /> | ||
| - | **[[1nul]], [[1grv]] - EcHPRT <br /> | + | **[[1nul]], [[1grv]], [[8cag]] - EcHPRT <br /> |
**[[1dbr]] - TgHPRT – ''Toxoplasma gondii''<br /> | **[[1dbr]] - TgHPRT – ''Toxoplasma gondii''<br /> | ||
**[[1tc1]] - TcHPRT – ''Trypanosoma cruzi''<br /> | **[[1tc1]] - TcHPRT – ''Trypanosoma cruzi''<br /> | ||
| Line 98: | Line 98: | ||
**[[3ggc]] - hHGPRT + hypoxanthine derivative<br /> | **[[3ggc]] - hHGPRT + hypoxanthine derivative<br /> | ||
| - | **[[4ijq]], [[4rab]], [[4rac]], [[4rad]], [[4ran]], [[4rao]], [[4raq]], [[6bnj]], | + | **[[4ijq]], [[4rab]], [[4rac]], [[4rad]], [[4ran]], [[4rao]], [[4raq]], [[6bnj]], [[5w8v]], [[5hia]], [[7san]] - hHGPRT + inhibitor<br /> |
**[[5bsk]], [[5brn]] - hHGPRT (mutant) + nucleoside phosphonate <br /> | **[[5bsk]], [[5brn]] - hHGPRT (mutant) + nucleoside phosphonate <br /> | ||
**[[4kn6]] - hHGPRT + antiviral agent<br /> | **[[4kn6]] - hHGPRT + antiviral agent<br /> | ||
| Line 109: | Line 109: | ||
**[[4z1o]] - SsHGPRT + PRPP - Sulfolobus solfataricus<br /> | **[[4z1o]] - SsHGPRT + PRPP - Sulfolobus solfataricus<br /> | ||
**[[6bo7]] - HGPRT + inhibitor – Plasmodium vivax<br /> | **[[6bo7]] - HGPRT + inhibitor – Plasmodium vivax<br /> | ||
| - | **[[6aqo]], [[6ar9]], [[6apv]], [[6apu]], [[6apt]], [[6aps]], [[5kap]], [[5k51]], [[5jsq]] - TbHGPRT + inhibitor <br /> | + | **[[6aqo]], [[6ar9]], [[6apv]], [[6apu]], [[6apt]], [[6aps]], [[5kap]], [[5k51]], [[5jsq]], [[7sb7]] - TbHGPRT + inhibitor <br /> |
*Hypoxanthine-guanine phosphoribosyltransferase ternary complex | *Hypoxanthine-guanine phosphoribosyltransferase ternary complex | ||
| Line 130: | Line 130: | ||
**[[5bqp]] - SsHGXPRT + pyrophosphate <br /> | **[[5bqp]] - SsHGXPRT + pyrophosphate <br /> | ||
**[[7kl6]], [[7kl7]] - HpHGXPRT <br /> | **[[7kl6]], [[7kl7]] - HpHGXPRT <br /> | ||
| + | **[[7tux]] - PfHGXPRT + inhibitor<br /> | ||
| + | **[[7scr]] - TbHGXPRT + inhibitor<br /> | ||
| + | **[[8fwy]] - TcHGXPRT + xanthine + Pi<br /> | ||
| + | **[[8fwz]], [[8fx0]], [[8fx1]], [[8fx2]], [[8fx3]] - TcHGXPRT + inhibitor<br /> | ||
*'''Quinolinic acid phosphoribosyltransferase''' | *'''Quinolinic acid phosphoribosyltransferase''' | ||
| Line 194: | Line 198: | ||
*Adenine phosphoribosyltransferase complex | *Adenine phosphoribosyltransferase complex | ||
| + | **[[7y94]] - hAPRT + adenine<br /> | ||
**[[1ore]], [[1zn8]], [[1zn9]], [[6fcl]] - hAPRT + AMP<br /> | **[[1ore]], [[1zn8]], [[1zn9]], [[6fcl]] - hAPRT + AMP<br /> | ||
**[[4x44]], [[4x45]] - hAPRT (mutant) + AMP <br /> | **[[4x44]], [[4x45]] - hAPRT (mutant) + AMP <br /> | ||
| Line 215: | Line 220: | ||
**[[1l1q]] - GiAPRT + adenine derivative<br /> | **[[1l1q]] - GiAPRT + adenine derivative<br /> | ||
**[[1l1r]] - GiAPRT + adenine derivative + PRPP<BR /> | **[[1l1r]] - GiAPRT + adenine derivative + PRPP<BR /> | ||
| + | **[[7xi2]] - EcAPRT + Pi<br /> | ||
*'''Nicotinate mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase''' | *'''Nicotinate mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase''' | ||
| Line 256: | Line 262: | ||
**[[4gtn]] – AcANPRT – ''Acinetobacter''<br /> | **[[4gtn]] – AcANPRT – ''Acinetobacter''<br /> | ||
**[[5nof]], [[5noe]] – ANPRT – ''Thermococcus kodkarensis''<br /> | **[[5nof]], [[5noe]] – ANPRT – ''Thermococcus kodkarensis''<br /> | ||
| + | **[[8bfr]] – EcANPRT<BR /> | ||
*Anthranilate phosphoribosyltransferase complex containing anthranilate | *Anthranilate phosphoribosyltransferase complex containing anthranilate | ||
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**[[1zvw]], [[5byt]], [[5c1r]], [[5c7s]] - MtANPRT + PRPP<BR /> | **[[1zvw]], [[5byt]], [[5c1r]], [[5c7s]] - MtANPRT + PRPP<BR /> | ||
**[[4x58]], [[4x59]], [[4x5b]] - MtANPRT (mutant) + PRPP<BR /> | **[[4x58]], [[4x59]], [[4x5b]] - MtANPRT (mutant) + PRPP<BR /> | ||
| + | **[[4ztv]], [[5bne]], [[5bo2]], [[5bo3]] - MtANPRT + inhibitor <BR /> | ||
| + | **[[3qqs]], [[3qs8]], [[3qsa]], [[3r6c]], [[3r88]], [[3twp]], [[3uu1]], [[4zof]], [[4zoj]], [[4zok]] - MtANPRT + inhibitor + PRPP<BR /> | ||
**[[4x5c]] - MtANPRT (mutant) + PRPP + POP<BR /> | **[[4x5c]] - MtANPRT (mutant) + PRPP + POP<BR /> | ||
**[[1zxy]] - SsANPRT + PRPP<BR /> | **[[1zxy]] - SsANPRT + PRPP<BR /> | ||
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**[[1gxb]] - SsANPRT + POP<br /> | **[[1gxb]] - SsANPRT + POP<br /> | ||
**[[2gvq]] - SsANPRT + anthranilate<br /> | **[[2gvq]] - SsANPRT + anthranilate<br /> | ||
| - | **[[ | + | **[[8bft]] - EcANPRT + OBGe peptide <BR /> |
| - | + | ||
*'''ATP phosphoribosyltransferase''' See [[ATP Phosphoribosyl Transferase]] | *'''ATP phosphoribosyltransferase''' See [[ATP Phosphoribosyl Transferase]] | ||
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**[[2gvj]] - hNMPRT + FK-866<br /> | **[[2gvj]] - hNMPRT + FK-866<br /> | ||
**[[2e5c]] - hNMPRT + PRPP<BR /> | **[[2e5c]] - hNMPRT + PRPP<BR /> | ||
| - | **[[2e5d]] - hNMPRT + nicotinamide<br /> | + | **[[2e5d]], [[8dsi]] - hNMPRT + nicotinamide<br /> |
**[[3dgr]] - hNMPRT + ADP analog<br /> | **[[3dgr]] - hNMPRT + ADP analog<br /> | ||
| - | **[[4jnm]], [[4jr5]], [[4kfn]], [[4kfo]], [[4kfp]], [[4lts]], [[4lv9]], [[4lva]], [[4lvb]], [[4lvd]], [[4lvf]], [[4lvg]], [[4lww]], [[4m6p]], [[4m6q]], [[4n9b]], [[4n9c]], [[4n9d]], [[4n9e]], [[4l4l]], [[4l4m]], [[4o0z]], [[4o10]], [[4o12]], [[4o13]], [[4o14]], [[4o15]], [[4o16]], [[4o17]], [[4o18]], [[4o19]], [[4o1a]], [[4o1b]], [[4o1c]], [[4o1d]], [[4wq6]], [[4o28]], [[5kit]], [[5u2m]], [[5u2n]], [[5upe]], [[5upf]], [[6e68]], [[5wi1]], [[5wi0]], [[6azj]], [[6b76]], [[6b75]], [[6atb]], [[6peb]], [[6tac]] - hNMPRT + inhibitor<br /> | + | **[[4jnm]], [[4jr5]], [[4kfn]], [[4kfo]], [[4kfp]], [[4lts]], [[4lv9]], [[4lva]], [[4lvb]], [[4lvd]], [[4lvf]], [[4lvg]], [[4lww]], [[4m6p]], [[4m6q]], [[4n9b]], [[4n9c]], [[4n9d]], [[4n9e]], [[4l4l]], [[4l4m]], [[4o0z]], [[4o10]], [[4o12]], [[4o13]], [[4o14]], [[4o15]], [[4o16]], [[4o17]], [[4o18]], [[4o19]], [[4o1a]], [[4o1b]], [[4o1c]], [[4o1d]], [[4wq6]], [[4o28]], [[5kit]], [[5u2m]], [[5u2n]], [[5upe]], [[5upf]], [[6e68]], [[5wi1]], [[5wi0]], [[6azj]], [[6b76]], [[6b75]], [[6atb]], [[6peb]], [[6tac]], [[7ppe]], [[7ppf]], [[7ppg]], [[7pph]], [[7ppi]], [[8dsm]] - hNMPRT + inhibitor<br /> |
| + | **[[7enq]], [[8dtj]] - hNMPRT + activator<br /> | ||
| + | **[[8dsc]], [[8dsd]] - hNMPRT + nicotinamide + activator<br /> | ||
| + | **[[8dsh]] - hNMPRT + AMPcP + activator<br /> | ||
**[[3dhd]], [[3dhf]] - hNMPRT + pyrophosphate + NMN<BR /> | **[[3dhd]], [[3dhf]] - hNMPRT + pyrophosphate + NMN<BR /> | ||
**[[3dkj]], [[3dkl]] - hNMPRT + benzamide + PRPP<BR /> | **[[3dkj]], [[3dkl]] - hNMPRT + benzamide + PRPP<BR /> | ||
Current revision
3D structures of phosphoribosyltransferase
Updated on 28-August-2023
