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1fx3

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[[Image:1fx3.gif|left|200px]]
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[[Image:1fx3.png|left|200px]]
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{{STRUCTURE_1fx3| PDB=1fx3 | SCENE= }}
{{STRUCTURE_1fx3| PDB=1fx3 | SCENE= }}
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'''CRYSTAL STRUCTURE OF H. INFLUENZAE SECB'''
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===CRYSTAL STRUCTURE OF H. INFLUENZAE SECB===
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==Overview==
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SecB is a bacterial molecular chaperone involved in mediating translocation of newly synthesized polypeptides across the cytoplasmic membrane of bacteria. The crystal structure of SecB from Haemophilus influenzae shows that the molecule is a tetramer organized as a dimer of dimers. Two long channels run along the side of the molecule. These are bounded by flexible loops and lined with conserved hydrophobic amino acids, which define a suitable environment for binding non-native polypeptides. The structure also reveals an acidic region on the top surface of the molecule, several residues of which have been implicated in binding to SecA, its downstream target.
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The line below this paragraph, {{ABSTRACT_PUBMED_11101901}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11101901 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11101901}}
==About this Structure==
==About this Structure==
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[[Category: Protein trasnport]]
[[Category: Protein trasnport]]
[[Category: Translocation]]
[[Category: Translocation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:51:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:04:41 2008''

Revision as of 01:04, 1 July 2008

Image:1fx3.png

Template:STRUCTURE 1fx3

CRYSTAL STRUCTURE OF H. INFLUENZAE SECB

Template:ABSTRACT PUBMED 11101901

About this Structure

1FX3 is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

Crystal structure of the bacterial protein export chaperone secB., Xu Z, Knafels JD, Yoshino K, Nat Struct Biol. 2000 Dec;7(12):1172-7. PMID:11101901

Page seeded by OCA on Tue Jul 1 04:04:41 2008

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