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2ztc

From Proteopedia

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Current revision (13:54, 1 November 2023) (edit) (undo)
 
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<StructureSection load='2ztc' size='340' side='right'caption='[[2ztc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2ztc' size='340' side='right'caption='[[2ztc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ztc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZTC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ztc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZTC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2h5x|2h5x]], [[2ztd|2ztd]], [[2zte|2zte]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ruvA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ztc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ztc OCA], [https://pdbe.org/2ztc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ztc RCSB], [https://www.ebi.ac.uk/pdbsum/2ztc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ztc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ztc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ztc OCA], [https://pdbe.org/2ztc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ztc RCSB], [https://www.ebi.ac.uk/pdbsum/2ztc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ztc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RUVA_MYCTU RUVA_MYCTU]] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity).
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[https://www.uniprot.org/uniprot/RUVA_MYCTU RUVA_MYCTU] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chandra, N R]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Khanduja, J S]]
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[[Category: Chandra NR]]
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[[Category: Muniyappa, K]]
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[[Category: Khanduja JS]]
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[[Category: Prabu, J R]]
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[[Category: Muniyappa K]]
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[[Category: Thamotharan, S]]
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[[Category: Prabu JR]]
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[[Category: Vijayan, M]]
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[[Category: Thamotharan S]]
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[[Category: Acidic pin]]
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[[Category: Vijayan M]]
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[[Category: Atp-binding]]
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[[Category: Branch migration]]
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[[Category: Dna binding]]
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[[Category: Dna binding protein]]
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[[Category: Dna damage]]
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[[Category: Dna recombination]]
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[[Category: Dna repair]]
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[[Category: Dna-binding]]
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[[Category: Helicase]]
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[[Category: Holliday junction]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide-binding]]
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[[Category: Oligomerization]]
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[[Category: Recombination]]
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[[Category: Sos response]]
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Current revision

MtRuvA Form II

PDB ID 2ztc

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