This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7v63
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Structure of dimeric uPAR at low pH== | ==Structure of dimeric uPAR at low pH== | ||
| - | <StructureSection load='7v63' size='340' side='right'caption='[[7v63]]' scene=''> | + | <StructureSection load='7v63' size='340' side='right'caption='[[7v63]], [[Resolution|resolution]] 2.91Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V63 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7v63]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V63 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v63 OCA], [https://pdbe.org/7v63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v63 RCSB], [https://www.ebi.ac.uk/pdbsum/7v63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v63 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v63 OCA], [https://pdbe.org/7v63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v63 RCSB], [https://www.ebi.ac.uk/pdbsum/7v63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v63 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/UPAR_HUMAN UPAR_HUMAN]] Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Huang M]] | + | [[Category: Huang, M]] |
| - | [[Category: Yuan C]] | + | [[Category: Yuan, C]] |
| + | [[Category: Gpi-anchored protein]] | ||
| + | [[Category: Immune system]] | ||
Current revision
Structure of dimeric uPAR at low pH
| |||||||||||
