This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2zzf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:03, 1 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2zzf' size='340' side='right'caption='[[2zzf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2zzf' size='340' side='right'caption='[[2zzf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2zzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZZF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2zzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZZF FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zze|2zze]], [[2zzg|2zzg]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alaS, PH0297, PH0297 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alanine--tRNA_ligase Alanine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.7 6.1.1.7] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zzf OCA], [https://pdbe.org/2zzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zzf RCSB], [https://www.ebi.ac.uk/pdbsum/2zzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zzf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zzf OCA], [https://pdbe.org/2zzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zzf RCSB], [https://www.ebi.ac.uk/pdbsum/2zzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zzf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/SYA_PYRHO SYA_PYRHO]] Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Edits incorrectly charged Ser-tRNA(Ala). Incorrectly charged amino acids occur because the of inherent physicochemical limitations on discrimination between closely related amino acids (Gly and Ser) in the charging step.<ref>PMID:16087889</ref>
+
[https://www.uniprot.org/uniprot/SYA_PYRHO SYA_PYRHO] Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Edits incorrectly charged Ser-tRNA(Ala). Incorrectly charged amino acids occur because the of inherent physicochemical limitations on discrimination between closely related amino acids (Gly and Ser) in the charging step.<ref>PMID:16087889</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 38: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Pyrococcus shinkaii]]
 
-
[[Category: Alanine--tRNA ligase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Nakamura, A]]
+
[[Category: Pyrococcus horikoshii]]
-
[[Category: Nureki, O]]
+
[[Category: Nakamura A]]
-
[[Category: Ose, T]]
+
[[Category: Nureki O]]
-
[[Category: Sokabe, M]]
+
[[Category: Ose T]]
-
[[Category: Tanaka, I]]
+
[[Category: Sokabe M]]
-
[[Category: Tokunaga, K]]
+
[[Category: Tanaka I]]
-
[[Category: Yao, M]]
+
[[Category: Tokunaga K]]
-
[[Category: Hydrolase]]
+
[[Category: Yao M]]
-
[[Category: Ligase]]
+

Current revision

Crystal structure of alanyl-tRNA synthetase without oligomerization domain

PDB ID 2zzf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zzf"
Personal tools