Inhibitory neurosteroids
From Proteopedia
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| - | + | These neurosteroids exert inhibitory actions on neurotransmission. They act as positive allosteric modulators of the [[GABAA receptor]] (especially δ subunit-containing isoforms), and possess, in no particular order, antidepressant, anxiolytic, stress-reducing, rewarding, prosocial, antiaggressive, prosexual, sedative, pro-sleep, cognitive and memory-impairing, analgesic, anesthetic, anticonvulsant, neuroprotective, and neurogenic effects. | |
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| - | + | Major examples include <scene name='89/896619/Cv/7'>tetrahydrodeoxycorticosterone</scene> (THDOC; from [[5osb]]), the androstane 3α-androstanediol, the cholestane cholesterol and the pregnanes pregnanolone (eltanolone), allopregnanolone (3α,5α-THP). | |
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 13:12, 26 December 2021
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