7l5a
From Proteopedia
(Difference between revisions)
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==Crystal structure of the photosensory module from Xanthomonas campestris bacteriophytochrome XccBphP in the Pfr state== | ==Crystal structure of the photosensory module from Xanthomonas campestris bacteriophytochrome XccBphP in the Pfr state== | ||
| - | <StructureSection load='7l5a' size='340' side='right'caption='[[7l5a]]' scene=''> | + | <StructureSection load='7l5a' size='340' side='right'caption='[[7l5a]], [[Resolution|resolution]] 2.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L5A FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7l5a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L5A FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l5a OCA], [https://pdbe.org/7l5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l5a RCSB], [https://www.ebi.ac.uk/pdbsum/7l5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l5a ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLA:BILIVERDINE+IX+ALPHA'>BLA</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l5a OCA], [https://pdbe.org/7l5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l5a RCSB], [https://www.ebi.ac.uk/pdbsum/7l5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l5a ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BPHY_XANC8 BPHY_XANC8]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: far-red light (733 nm) converts protein to the red-absorbing (Pr) form, while red light (630 nm) partly converts the protein to the far-red-absorbing (Pfr) form (PubMed:27107635). Regulates virulence of X.campestris pv. campestris on its host plants, perhaps by fine-tuning expression to ambient light levels and/or spatial cues (PubMed:27621284). The Pr form may sense light and partially inhibit virulence; in the dark (Pfr form) biofilm and xanathan production rise and bacteria are more virulent (PubMed:27621284). Strains overexpressing this protein have significantly decreased amounts of extracellular beta-1,4-endoglucanase, produce less xanthin and have decreased transcription of genes involved in virulence such as endoglucanases, type 2 secretion systems, xanthan production and flagellar-dependent motility (PubMed:27621284).<ref>PMID:27107635</ref> <ref>PMID:27621284</ref> <ref>PMID:27621284</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | [Figure: see text]. | ||
| + | |||
| + | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.,Otero LH, Foscaldi S, Antelo GT, Rosano GL, Sirigu S, Klinke S, Defelipe LA, Sanchez-Lamas M, Battocchio G, Conforte V, Vojnov AA, Chavas LMG, Goldbaum FA, Mroginski MA, Rinaldi J, Bonomi HR Sci Adv. 2021 Nov 26;7(48):eabh1097. doi: 10.1126/sciadv.abh1097. Epub 2021 Nov, 24. PMID:34818032<ref>PMID:34818032</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7l5a" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Antelo G]] | + | [[Category: Antelo, G]] |
| - | [[Category: Bonomi | + | [[Category: Bonomi, H R]] |
| - | [[Category: Goldbaum | + | [[Category: Goldbaum, F A]] |
| - | [[Category: Klinke S]] | + | [[Category: Klinke, S]] |
| - | [[Category: Otero | + | [[Category: Otero, L H]] |
| - | [[Category: Rinaldi J]] | + | [[Category: Rinaldi, J]] |
| - | [[Category: Sanchez-Lamas M]] | + | [[Category: Sanchez-Lamas, M]] |
| + | [[Category: Bacterial protein]] | ||
| + | [[Category: Photoreceptor]] | ||
| + | [[Category: Photosensor]] | ||
| + | [[Category: Phytochrome]] | ||
| + | [[Category: Phytopathogen]] | ||
| + | [[Category: Red/far-red light]] | ||
| + | [[Category: Signal transduction]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 05:24, 13 July 2022
Crystal structure of the photosensory module from Xanthomonas campestris bacteriophytochrome XccBphP in the Pfr state
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