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2ftp
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ftp' size='340' side='right'caption='[[2ftp]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2ftp' size='340' side='right'caption='[[2ftp]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ftp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2ftp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FTP FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ftp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ftp OCA], [https://pdbe.org/2ftp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ftp RCSB], [https://www.ebi.ac.uk/pdbsum/2ftp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ftp ProSAT], [https://www.topsan.org/Proteins/MCSG/2ftp TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ftp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ftp OCA], [https://pdbe.org/2ftp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ftp RCSB], [https://www.ebi.ac.uk/pdbsum/2ftp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ftp ProSAT], [https://www.topsan.org/Proteins/MCSG/2ftp TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIUE_PSEAE LIUE_PSEAE] Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate.<ref>PMID:19459965</ref> <ref>PMID:19597963</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ftp ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ftp ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Hydroxymethylglutaryl-CoA lyase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa PAO1]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Evdokimova | + | [[Category: Evdokimova E]] |
| - | [[Category: Kudritska | + | [[Category: Kudritska M]] |
| - | [[Category: Liu | + | [[Category: Liu Y]] |
| - | + | [[Category: Pai EF]] | |
| - | [[Category: Pai | + | [[Category: Savchenko A]] |
| - | [[Category: Savchenko | + | [[Category: Xiao T]] |
| - | [[Category: Xiao | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa
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